Fluorescent probes for imaging in humans: where are we now?

D Seah, Z Cheng, M Vendrell - ACS nano, 2023 - ACS Publications
Optical imaging has become an indispensable technology in the clinic. The molecular
design of cell-targeted and highly sensitive materials, the validation of specific disease …

Augmented reality for the surgeon: systematic review

JW Yoon, RE Chen, EJ Kim… - … journal of medical …, 2018 - Wiley Online Library
Introduction Since the introduction of wearable head‐up displays, there has been much
interest in the surgical community adapting this technology into routine surgical practice …

Head-mounted display use in surgery: a systematic review

R Rahman, ME Wood, L Qian, CL Price… - Surgical …, 2020 - journals.sagepub.com
Purpose. We analyzed the literature to determine (1) the surgically relevant applications for
which head-mounted display (HMD) use is reported;(2) the types of HMD most commonly …

Bio-inspired color-polarization imager for real-time in situ imaging

M Garcia, C Edmiston, R Marinov, A Vail, V Gruev - Optica, 2017 - opg.optica.org
Nature has a large repertoire of animals that take advantage of naturally abundant
polarization phenomena. Among them, the mantis shrimp possesses one of the most …

Current trends and key considerations in the clinical translation of targeted fluorescent probes for intraoperative navigation

R Liu, Y Xu, K Xu, Z Dai - Aggregate, 2021 - Wiley Online Library
The rapid development of fluorescence imaging for intraoperative navigation has spurred
further development of targeted fluorescent probes in the past decade. Only a few …

Perspective review of what is needed for molecular-specific fluorescence-guided surgery

BW Pogue, EL Rosenthal, S Achilefu… - … of biomedical optics, 2018 - spiedigitallibrary.org
Molecular image-guided surgery has the potential for translating the tools of molecular
pathology to real-time guidance in surgery. As a whole, there are incredibly positive …

Detecting the near infrared autofluorescence of the human parathyroid: hype or opportunity?

CC Solórzano, G Thomas, N Baregamian… - Annals of …, 2020 - journals.lww.com
Objective: With the recent approval of 2 NIRAF-based devices for label-free identification of
PG by the Food and Drug Administration, it becomes crucial to educate the surgical …

Targeted optical imaging agents in cancer: focus on clinical applications

BP Joshi, TD Wang - Contrast media & molecular imaging, 2018 - Wiley Online Library
Molecular imaging is an emerging strategy for in vivo visualization of cancer over time based
on biological mechanisms of disease activity. Optical imaging methods offer a number of …

Emerging intraoperative imaging modalities to improve surgical precision

IS Alam, I Steinberg, O Vermesh… - Molecular Imaging and …, 2018 - Springer
Intraoperative imaging (IOI) is performed to guide delineation and localization of regions of
surgical interest. While oncological surgical planning predominantly utilizes x-ray computed …

Real-time diagnosis and visualization of tumor margins in excised breast specimens using fluorescence lifetime imaging and machine learning

J Unger, C Hebisch, JE Phipps, JL Lagarto… - Biomedical optics …, 2020 - opg.optica.org
Tumor-free surgical margins are critical in breast-conserving surgery. In up to 38% of the
cases, however, patients undergo a second surgery since malignant cells are found at the …