Examining the quaternary ammonium chitosan Schiff base-ZnO nanocomposite's potential as protective therapy for rats' cisplatin-induced hepatotoxicity

ES Kotb, HW Alhamdi, MY Alfaifi, O Darweesh… - International Journal of …, 2024 - Elsevier
Background Despite cisplatin's long history as a cornerstone in cancer therapy, both
acquired chemoresistance and significant impacts on healthy tissues limit its use …

Co-administration of either curcumin or resveratrol with cisplatin treatment decreases hepatotoxicity in rats via anti-inflammatory and oxidative stress-apoptotic …

OI Ramadan, LS Ali, FM Abd-Allah, REA Ereba… - PeerJ, 2024 - peerj.com
Background Cisplatin (CIS) is a broad-spectrum anticancer drug, with cytotoxic effects on
either malignant or normal cells. We aimed to evaluate the hepatotoxicity in rats caused by …

The possible protective role of platelet-rich plasma against cisplatin-induced hepatotoxicity in rat model

AH Mohamed, HAELD Mubarak, SS Anwer… - Aswan University …, 2023 - journals.ekb.eg
Background: Cisplatin (CP) is a potent chemotherapeutic agent used to treat a variety of
cancers The major limiting side effect of cisplatin is its hepatotoxicity. The mechanism of …