Loss of estrogens or androgens increases the rate of bone remodeling by removing
restraining effects on osteoblastogenesis and osteoclastogenesis, and also causes a focal …

Androgens are not only essential for bone development but for the maintenance of bone
mass. Therefore, conditions with androgen deficiency, such as male hypogonadism …

Androgens have important effects on the human skeleton, and deficiency has been
associated with bone loss in both males and females. The skeletal actions of androgens …

The skeleton is a complex tissue, and hormonal control of bone remodelling is elaborate.
The important role that steroid hormones play in bone cell development and in the …

Androgens play a key role in the maintenance of male skeletal integrity. The regulation of
this integrity by androgen receptor (AR) signaling has been mainly attributed to osteoblasts …

Glucocorticoids are used for treating a wide range of diseases including inflammation and
autoimmune disorders. However, there are drawbacks, primarily due to adverse effects on …

Osteoporosis is a common skeletal disease characterized by low bone mass and
microarchitectural deterioration of bone tissue with a consequent increase in bone fragility …

Androgens have beneficial effects on skeletal development and maintenance in women and
men. The detection and functional characterization of androgen receptors in bone cells has …

There are obvious sexual differences in adult skeletal morphology which for the most part
are related to differences in size. Higher androgen serum levels in males exert potent …

Androgen receptors are present at low densities in osteoblasts. Androgens are also
metabolized in bone.(Non) aromatizable androgens probably induce proliferation of …