GAL4 interacts with TATA-binding protein and coactivators
K Melcher, SA Johnston - Molecular and cellular biology, 1995 - Taylor & Francis
A major goal in understanding eukaryotic gene regulation is to identify the target (s) of
transcriptional activators. Efforts to date have pointed to various candidates. Here we show …
transcriptional activators. Efforts to date have pointed to various candidates. Here we show …
[HTML][HTML] Host virus interactions and the molecular regulation of HIV-1: role in the pathogenesis of HIV-associated nephropathy
J Rappaport, JB Kopp, PE Klotman - Kidney international, 1994 - Elsevier
Chronic renal disease affects up to 10% of children and adults with HIV infection, and is
manifested by a characteristic syndrome that has been termed HIV-associated nephropathy …
manifested by a characteristic syndrome that has been termed HIV-associated nephropathy …
The strength of acidic activation domains correlates with their affinity for both transcriptional and non-transcriptional proteins
K Melcher - Journal of molecular biology, 2000 - Elsevier
Activation domains (ADs) appear to work by making specific protein-protein contacts with the
transcriptional machinery. However, ADs show no apparent sequence conservation, they …
transcriptional machinery. However, ADs show no apparent sequence conservation, they …
Fab′-induced folding of antigenic N-terminal peptides from intrinsically disordered HIV-1 Tat revealed by X-ray crystallography
J Serrière, JM Dugua, M Bossus, B Verrier… - Journal of molecular …, 2011 - Elsevier
Tat, the transcriptional activator protein of human immunodeficiency virus type 1 (HIV-1), is
critical for viral replication and is a potential HIV-1 vaccine candidate. This intrinsically …
critical for viral replication and is a potential HIV-1 vaccine candidate. This intrinsically …
The amino terminal deletion mutants of hepatitis C virus nonstructural protein NS5A function as transcriptional activators in yeast
A Tanimoto, Y Ide, N Arima, Y Sasaguri… - Biochemical and …, 1997 - Elsevier
To investigate the biological function of hepatitis C virus (HCV)-NS5A, the NS5A was fused
at its N-terminus with the DNA binding domain (DBD) of yeast transcriptional activator GAL4 …
at its N-terminus with the DNA binding domain (DBD) of yeast transcriptional activator GAL4 …
Enterovirus type 71 2A protease functions as a transcriptional activator in yeast
CH Yang, HC Li, JG Jiang, CF Hsu, YJ Wang… - Journal of biomedical …, 2010 - Springer
Abstract Enterovirus type 71 (EV71) 2A protease exhibited strong transcriptional activity in
yeast cells. The transcriptional activity of 2A protease was independent of its protease …
yeast cells. The transcriptional activity of 2A protease was independent of its protease …
Inhibition of human immunodeficiency virus type 1 and type 2 Tat function by transdominant Tat protein localized to both the nucleus and cytoplasm
MJ Orsini, CM Debouck - Journal of virology, 1996 - Am Soc Microbiol
We introduced various mutations into the activation and RNA binding domains of human
immunodeficiency virus type 1 (HIV-1) Tat in order to develop a novel and potent …
immunodeficiency virus type 1 (HIV-1) Tat in order to develop a novel and potent …
Overexpression of PRMT6 does not suppress HIV-1 Tat transactivation in cells naturally lacking PRMT6
H Sivakumaran, MH Lin, A Apolloni, V Cutillas, H Jin… - Virology journal, 2013 - Springer
Background Protein arginine methyltransferase 6 (PRMT6) can methylate the HIV-1 Tat, Rev
and nucleocapsid proteins in a manner that diminishes each of their functions in in vitro …
and nucleocapsid proteins in a manner that diminishes each of their functions in in vitro …
Genetic diversity of simian immunodeficiency viruses from West African green monkeys: evidence of multiple genotypes within populations from the same …
F Bibollet-Ruche, C Brengues, A Galat-Luong… - Journal of …, 1997 - Am Soc Microbiol
High simian immunodeficiency virus (SIV) seroprevalence rates have been reported in the
different African green monkey (AGM) subspecies. Genetic diversity of these viruses far …
different African green monkey (AGM) subspecies. Genetic diversity of these viruses far …
Sequence variation within the dominant amino terminus epitope affects antibody binding and neutralization of human immunodeficiency virus type 1 Tat protein
TJ Ruckwardt, I Tikhonov, S Berg, GS Hatfield… - Journal of …, 2004 - Am Soc Microbiol
Tat is among the required regulatory genes of human immunodeficiency virus type 1 (HIV-1).
Tat functions both within infected cells as a transcription factor and as an extracellular factor …
Tat functions both within infected cells as a transcription factor and as an extracellular factor …