The pathophysiology of heart failure (HF) is characterized by hemodynamic abnormalities that result in neurohormonal activation and autonomic imbalance with increase in …
K Sharma, DA Kass - Circulation research, 2014 - Am Heart Assoc
The clinical syndrome comprising heart failure (HF) symptoms but with a left ventricular ejection fraction (EF) that is not diminished, eg, HF with preserved EF, is increasingly the …
S Oparil, RE Schmieder - Circulation research, 2015 - Am Heart Assoc
Hypertension is the most common modifiable risk factor for cardiovascular disease and death, and lowering blood pressure with antihypertensive drugs reduces target organ …
Objectives: We sought to determine the effect of baroreflex activation therapy (BAT) on systolic blood pressure (SBP) in patients with resistant hypertension. Background: The …
UC Hoppe, MC Brandt, R Wachter, J Beige… - Journal of the American …, 2012 - Elsevier
BACKGROUND: Previous trials have demonstrated clinically significant and durable reductions in arterial pressure from baroreflex activation therapy (BAT), resulting from …
A neurogenic component to primary hypertension (hypertension) is now well established. Along with raised vasomotor tone and increased cardiac output, the chronic activation of the …
One of the main reasons why drug adherence remains generally ignored, outside of clinical trials and prospective surveys, is the lack of reliable, easy to use, and economical methods …
DH Lau, U Schotten, R Mahajan, NA Antic… - European heart …, 2016 - academic.oup.com
Intensive research over the last few decades has seen significant advances in our understanding of the complex mechanisms underlying atrial fibrillation (AF). The epidemic of …
L Lauder, M Azizi, AJ Kirtane, M Boehm… - Nature Reviews …, 2020 - nature.com
Arterial hypertension is the most prevalent modifiable risk factor associated with cardiovascular morbidity and mortality. Although antihypertensive drugs are widely …