Cu (I)-catalyzed click chemistry in glycoscience and their diverse applications

AK Agrahari, P Bose, MK Jaiswal, S Rajkhowa… - Chemical …, 2021 - ACS Publications
Copper (I)-catalyzed 1, 3-dipolar cycloaddition between organic azides and terminal
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …

Triazole derivatives and their anti-tubercular activity

S Zhang, Z Xu, C Gao, QC Ren, L Chang, ZS Lv… - European journal of …, 2017 - Elsevier
Tuberculosis (TB) remains one of the most widespread and leading deadliest diseases,
threats one-third of the world's population. Although numerous efforts have been undertaken …

Cu-catalyzed click reaction in carbohydrate chemistry

VK Tiwari, BB Mishra, KB Mishra, N Mishra… - Chemical …, 2016 - ACS Publications
Cu (I)-catalyzed azide–alkyne 1, 3-dipolar cycloaddition (CuAAC), popularly known as the
“click reaction”, serves as the most potent and highly dependable tool for facile construction …

Click chemistry: 1, 2, 3‐triazoles as pharmacophores

SG Agalave, SR Maujan… - Chemistry–An Asian …, 2011 - Wiley Online Library
Abstract The copper (I)‐catalyzed 1, 2, 3‐triazole‐forming reaction between azides and
terminal alkynes has become the gold standard of 'click chemistry'due to its reliability …

Recent researches in triazole compounds as medicinal drugs

C -H. Zhou, Y Wang - Current medicinal chemistry, 2012 - benthamdirect.com
Triazole compounds containing three nitrogen atoms in the five-membered aromatic azole
ring are readily able to bind with a variety of enzymes and receptors in biological system via …

Recent applications of photoredox catalysis in O-heterocycles: A short review

PP Singh, PK Singh, MZ Beg, A Kashyap… - Synthetic …, 2021 - Taylor & Francis
The oxygenated heterocycles are widely found in natural products, medicinal molecules,
and various multifunctional components. A large number of synthetic methods have been …

Direct access to 1, 2, 3-triazoles through organocatalytic 1, 3-dipolar cycloaddition reaction of allyl ketones with azides

W Li, Z Du, J Huang, Q Jia, K Zhang, J Wang - Green Chemistry, 2014 - pubs.rsc.org
Direct access to 1,2,3-triazoles through organocatalytic 1,3-dipolar cycloaddition reaction of
allyl ketones with azides - Green Chemistry (RSC Publishing) DOI:10.1039/C4GC00406J …

O‐GlcNAcase: Emerging Mechanism, Substrate Recognition and Small‐Molecule Inhibitors

AA Elbatrawy, EJ Kim, G Nam - ChemMedChem, 2020 - Wiley Online Library
O‐GlcNAcylation is the dynamic and ubiquitous post‐translational glycosylation of
nucleocytoplasmic proteins on serine/threonine residues; it is implicated in regulation of the …

Antimicrobial and cytotoxic activities of 1, 2, 3-triazole-sucrose derivatives

KT Petrova, TM Potewar, P Correia-da-Silva… - Carbohydrate …, 2015 - Elsevier
Abstract A library of 1-(1′, 2, 3, 3′, 4, 4′, 6-hepta-O-acetyl-6′-deoxy-sucros-6′-yl)-1, 2,
3-triazoles have been investigated for their antibacterial, antifungal and cytotoxic activities …

Recent trends in 1, 2, 3-triazolo-nucleosides as promising anti-infective and anticancer agents

S Raic-Malic, A Mescic - Current medicinal chemistry, 2015 - ingentaconnect.com
The concept of click chemistry represented by the formation of the 1, 2, 3-triazole core has
found wide application in drug discovery, particularly in the early discovery phases and the …