Breakthroughs in hepatitis C research: from discovery to cure

MP Manns, B Maasoumy - Nature reviews Gastroenterology & …, 2022 - nature.com
In the 1970s, an unknown virus was suspected for documented cases of transfusion-
associated hepatitis, a phenomenon called non-A, non-B hepatitis. In 1989, the infectious …

Interventions to enhance testing, linkage to care, and treatment initiation for hepatitis C virus infection: a systematic review and meta-analysis

EB Cunningham, A Wheeler, B Hajarizadeh… - The lancet …, 2022 - thelancet.com
Background Despite the goal set by WHO to eliminate hepatitis C virus (HCV) as a public
health threat, uptake of HCV testing and treatment remains low. To achieve this target …

Progress towards elimination goals for viral hepatitis

AL Cox, MH El-Sayed, JH Kao, JV Lazarus… - Nature reviews …, 2020 - nature.com
The global burden of viral hepatitis is substantial; in terms of mortality, hepatitis B virus and
hepatitis C virus infections are on a par with HIV, malaria and tuberculosis, among the top …

Reflex hepatitis C virus viral load testing following an initial positive hepatitis C virus antibody test: A global systematic review and meta-analysis

Y Tao, W Tang, E Fajardo, M Cheng… - Clinical Infectious …, 2023 - academic.oup.com
Background Many people who have a positive hepatitis C virus (HCV) antibody (Ab) test
never receive a confirmatory HCV RNA viral load (VL) test. Reflex VL testing may help …

Global cascade of care for chronic hepatitis C virus infection: A systematic review and meta‐analysis

MT Yousafzai, S Bajis, M Alavi, J Grebely… - Journal of viral …, 2021 - Wiley Online Library
Abstract The World Health Organization 2030 targets for hepatitis C virus (HCV) elimination
include diagnosing 90% of people with HCV and treating 80% of people diagnosed with …

Global treatment rate and barriers to direct‐acting antiviral therapy: a systematic review and meta‐analysis of 146 studies and 1 760 352 hepatitis C virus patients

VH Nguyen, DQ Huang, MH Le, M Jin, EY Lee… - Liver …, 2023 - Wiley Online Library
Background Global data on the treatment rate with direct‐acting antivirals (DAAs) for chronic
hepatitis C (CHC) are sparse. We aimed to evaluate the CHC treatment rate and barriers to …

Hepatitis C diagnosis: simplified solutions, predictive barriers, and future promises

I Shahid, AR Alzahrani, SS Al-Ghamdi, IM Alanazi… - Diagnostics, 2021 - mdpi.com
The simplification of current hepatitis C diagnostic algorithms and the emergence of digital
diagnostic devices will be very crucial to achieving the WHO's set goals of hepatitis C …

[HTML][HTML] Insights from a national survey in 2021 and from modelling on progress towards hepatitis C virus elimination in the country of Georgia since 2015

JG Walker, I Tskhomelidze, S Shadaker… - …, 2023 - eurosurveillance.org
Background Between May 2015 and February 2022, 77,168 hepatitis C virus (HCV)-infected
people in Georgia have been treated through an HCV elimination programme. To project the …

[HTML][HTML] Risky sexual practices and hepatitis C viremia among HIV-positive men who have sex with men in Taiwan

MH Huang, GJ Chen, HY Sun, YT Chen, LH Su… - Journal of Microbiology …, 2023 - Elsevier
Background Understanding the risk behaviors associated with sexually-transmitted hepatitis
C virus (HCV) infection among men who have sex with men (MSM) may inform the public …

Feasibility and effectiveness of HCV viraemia testing at harm reduction sites in Georgia: A prospective three‐arm study

S Shilton, J Markby, M Japaridze, V Chihota… - Liver …, 2022 - Wiley Online Library
Abstract Background and Aims In 2015, Georgia began a hepatitis C virus (HCV) elimination
programme. Although screening programmes have been decentralized for high‐risk groups …