Simple Summary The tumor microenvironment is a complex network comprised of
neoplastic and a variety of immune cells, proteins, and inflammatory mediators. Previous …

Breast cancer is the most common cancer affecting women and is the second leading cause
of cancer related death worldwide. Angiogenesis, the process of new blood vessel …

An early diagnosis and precise prognosis are critical for the treatment of glioma. The
mitogen‑activated protein kinase (MAPK) signaling pathway potentially affects glioma, but …

Background Resistance to temozolomide (TMZ) is a major obstacle to preventing
glioblastoma (GBM) recurrence after surgery. Although long noncoding RNAs (lncRNAs) …

Circadian rhythms regulate various processes in the human body, including drug
metabolism. Chronotherapy optimizes treatment timing based on the circadian rhythm of the …

Gliomas are extremely debilitating malignant brain tumors with very limited response to
therapies. The initiation and progression of gliomas can be attributed to several molecular …

Significance: Risk factors in the environment such as air pollution and traffic noise contribute
to the development of chronic noncommunicable diseases. Recent Advances …

Background Chronotherapy is an innovative approach to improving survival through timed
delivery of anti-cancer treatments according to patient daily rhythms. Temozolomide (TMZ) is …

Preclinical models provided ample evidence that cannabinoids are cytotoxic against cancer
cells. Among the best studied phytocannabinoids, cannabidiol (CBD) is most promising for …

Neuropathological lesions in Alzheimer's disease (AD) include amyloid plaques formed by
the accumulation of amyloid peptides, neurofibrillary tangles made of hyperphosphorylated …