The dynamic interplay between cellular immunity and tumor cells is essential in cancer advancement and response to therapy. This updated, comprehensive review examines the …
Functional polymorphisms in promoter regions can produce changes in the affinity of transcription factors, thus altering the messenger ribonucleic acid (mRNA) expression levels …
Y Xia, CC Huang, R Dittmar, M Du, Y Wang, H Liu… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Genetic profiling of urine cell free DNA (cfDNA) has not been evaluated in advanced prostate cancer. We performed whole genome sequencing of urine cfDNAs to identify tumor …
Background Hepatocellular carcinoma (HCC) is one of the most prevalent types of cancer and is responsible for close to one million annual deaths globally. In Pakistan, HCC …
EM Johnson, DC Daniel… - Journal of cellular …, 2013 - Wiley Online Library
The Pur proteins are an ancient family of sequence‐specific single‐stranded nucleic acid‐ binding proteins. They bind a G‐rich element in either single‐or double‐stranded nucleic …
Gastric carcinoma is one of the most widespread malignancies worldwide. Interleukins are the key group of cytokines which may have tumor-promoting or tumor-suppressing effect …
AS Qaseem, S Sonar, L Mahajan, T Madan… - Molecular …, 2013 - Elsevier
Surfactant protein D (SP-D) is an innate immune molecule that plays a protective role against lung infection, allergy, asthma and inflammation. In vivo experiments with murine …
D Dietrich, S Meller, B Uhl, B Ralla… - Critical reviews in …, 2014 - Taylor & Francis
Molecular biomarkers play an important role in the clinical management of cancer patients. Biomarkers allow estimation of the risk of developing cancer; help to diagnose a tumor …
R Okada, K Wakai, M Naito, E Morita, S Kawai… - BMC nephrology, 2012 - Springer
Background The aim of this study was to explore the associations between common potential functional promoter polymorphisms in pro-/anti-inflammatory cytokine genes and …