IntelliCage: the development and perspectives of a mouse-and user-friendly automated behavioral test system

HP Lipp, S Krackow, E Turkes, S Benner… - Frontiers in Behavioral …, 2024 - frontiersin.org
IntelliCage for mice is a rodent home-cage equipped with four corner structures harboring
symmetrical double panels for operant conditioning at each of the two sides, either by …

Active reinforcement learning versus action bias and hysteresis: control with a mixture of experts and nonexperts

JT Colas, JP O'Doherty, ST Grafton - PLOS Computational Biology, 2024 - journals.plos.org
Active reinforcement learning enables dynamic prediction and control, where one should not
only maximize rewards but also minimize costs such as of inference, decisions, actions, and …

Enhancement of Mediodorsal Thalamus Rescues Aberrant Belief Dynamics in a Novel Mouse Model for Schizophrenia

T Zhou, YY Ho, RX Lee, AB Fath, K He, J Scott… - bioRxiv, 2024 - biorxiv.org
Optimizing behavioral strategy requires belief updating based on new evidence, a process
that engages higher cognition. In schizophrenia, aberrant belief dynamics may lead to …

Diverse and flexible behavioral strategies arise in recurrent neural networks trained on multisensory decision making

T Wierda, S Dora, CMA Pennartz, JF Mejias - bioRxiv, 2023 - biorxiv.org
Behavioral variability across individuals leads to substantial performance differences during
cognitive tasks, although its neuronal origin and mechanisms remain elusive. Here we use …

An agent-based model of behaviour change calibrated to reversal learning data

RD Reyes, HL Keenan, C Zachreson - arXiv preprint arXiv:2406.14062, 2024 - arxiv.org
Behaviour change lies at the heart of many observable collective phenomena such as the
transmission and control of infectious diseases, adoption of public health policies, and …

L (M) V-IQL: Multiple Intention Inverse Reinforcement Learning for Animal Behavior Characterization

H Zhu, B De La Crompe, G Kalweit, A Schneider… - arXiv preprint arXiv …, 2023 - arxiv.org
In advancing the understanding of decision-making processes, mathematical models,
particularly Inverse Reinforcement Learning (IRL), have proven instrumental in …

[HTML][HTML] Enhancement of mediodorsal thalamus rescues aberrant belief dynamics in a mouse model with schizophrenia-associated mutation

T Zhou, YY Ho, RX Lee, AB Fath, K He, J Scott… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Optimizing behavioral strategy requires belief updating based on new evidence, a process
that engages higher cognition. In schizophrenia, aberrant belief dynamics may lead to …

Dorsal prefrontal cortex drives perseverative behavior in mice

A Lebedeva, Y Wang, L Funnell, B Terry, J Oh, K Miller… - bioRxiv, 2024 - biorxiv.org
Perseveration--repeating one choice when others would generate larger rewards--is a
common behavior, but neither its purpose nor neuronal mechanisms are understood. Here …

Dynamic reinforcement learning reveals time-dependent shifts in strategy during reward learning

SJC Venditto, KJ Miller, CD Brody, ND Daw - bioRxiv, 2024 - biorxiv.org
Different brain systems have been hypothesized to subserve multiple “experts” that compete
to generate behavior. In reinforcement learning, two general processes, one model-free …

Neural networks representing temporal expectation in mice

AT Wendlandt, P Wenk, JU Henschke, A Michalek… - bioRxiv, 2024 - biorxiv.org
The ability to attend to specific moments in time is crucial for survival across species
facilitating perception and motor performance by leveraging prior temporal knowledge for …