Over the past three decades, a considerable body of evidence has highlighted T cells as
pivotal culprits in the pathogenesis of psoriasis. This includes the association of psoriasis …

Psoriasis is one of the most common immune-mediated chronic, inflammatory skin diseases
characterized by hyperproliferative keratinocytes and infiltration of T cells, dendritic cells …

Psoriasis is a common and chronic inflammatory skin disease in which T cells play a key
role. Effective treatment heals the skin without scarring, but typically psoriasis recurs in …

Background Plaque psoriasis is a chronic and often debilitating skin disorder and
proinflammatory cytokines are known to play a key role in the disease process. Objectives …

Psoriasis can be provoked or exacerbated by a variety of different environmental factors,
particularly infections and drugs. Strong evidence exists for the induction of guttate psoriasis …

Since the foundation of the European Society for Dermatological Research, pathogenesis of
psoriasis has been studied by many research groups, focusing on various compartments of …

Establishing direct and causal relationships among the confederacy of activated cell types
present in psoriasis has been hampered by lack of an animal model. Within psoriatic …

Psoriasis is strongly associated with streptococcal throat infection, and patients have
increased occurrence of such infections. Psoriatic lesional T cells are oligoclonal, and T …

A central tenet of the T-cell hypothesis of psoriasis is that lymphocytes can change
epidermal growth homeostasis, leading to increased keratinocyte proliferation and abnormal …

Psoriasis is an immune‐mediated skin disease characterized by lymphocytic infiltration and
altered keratinocyte differentiation. Using immunohistochemical techniques we found that …