Mounting an immune response is an energy-consuming process. Activating immune
functions requires the synthesis of many new molecules and the undertaking of numerous …

Being overweight increases the risk of many metabolic disorders, but how it affects lifespan
is not completely clear. Not all obese people become ill, and the exact mechanism that turns …

Macrophage-mediated phagocytosis and cytokine production represent the front lines of
resistance to bacterial invaders. A key feature of this pro-inflammatory response in mammals …

The thriving field that constitutes cancer metabolism has unveiled some groundbreaking
facts over the past two decades, at the heart of which is the TCA cycle and its intermediates …

Multicellular organisms live in environments containing diverse nutrients and a wide variety
of microbial communities. On the one hand, the immune response of organisms can protect …

Cancer has joined heart disease as the leading source of mortality in the US. In an era of
organoids, patient-derived xenografts, and organs on a chip, model organisms continue to …

Cancer cells usually exhibit aberrant cell signaling and metabolic reprogramming. However,
mechanisms of crosstalk between these processes remain elusive. Here, we show that in an …

Mutations or dysregulated expression of NF-kappaB-activating protein (NKAP) family genes
have been found in human cancers. How NKAP family gene mutations promote tumor …

Tumor growth and progression involve coordinated regulation by internal,
microenvironmental, and systemic signals and often display conspicuous sexual …

Geometric morphometrics analysis (GMA) is a well-known technique to identify minute
changes in Drosophila wings. This study aimed to determine potential changes in …