DNA methylation of cytosines in CpG sites throughout the genome is an epigenetic mark
contributing to gene expression regulation. DNA methylation patterns are specific to tissue …

Although primary central nervous system (CNS) tumors account for only 2% of all primary
cancers, they cause 7% of deaths from cancer in those younger than 70 years old. 1 Median …

Purpose: The immunosuppressive tumor microenvironment present in the majority of diffuse
glioma limits therapeutic response to immunotherapy. As the determinants of the glioma …

Brain tumors are the leading cause of morbidity and mortality related to cancer in children,
where high-grade glioma harbor the worst prognosis. It has become obvious that pediatric …

Diffusely infiltrating gliomas are among the most common central nervous system tumors in
adults. Over the past decade, the subcategorization of these tumors has changed to include …

Diffuse spinal cord gliomas (SCGs) are rare tumors associated with a high morbidity and
mortality that affect both pediatric and adult populations. In this retrospective study, we …

Glioblastoma (GBM) is the most common malignant primary central nervous system (CNS)
neoplasm in adults, and has an almost universally poor prognosis. Recently, an emphasis …

Simple Summary Pediatric brain tumors are unique from adult tumors and pose challenges
due to their distinct characteristics, including differences in tumor immunology, molecular …

Resumen Introducción: El Xantoastrocitoma Pleomórfico (XAP) es un tumor cerebral raro y
generalmente de bajo grado, que se presenta con desafíos significativos en su diagnóstico …

Tumors of central nervous system (CNS) are the second most frequent type of neoplasms in
children and adults, the primary tumors of the CNS being the leading cause of death in these …