[HTML][HTML] Exploring the concept of psychological frailty in older adults: a systematic scoping review
Objectives We reviewed the existing definitions of psychological frailty and provided a
comprehensive overview of the concept and associated measurements. Study Design and …
comprehensive overview of the concept and associated measurements. Study Design and …
Frailty and cardiovascular health
The incidence of frailty and cardiovascular disease (CVD) increases as the population ages.
There is a bidirectional relationship between frailty and CVD, and both conditions share …
There is a bidirectional relationship between frailty and CVD, and both conditions share …
A metabolomic profile of biological aging in 250,341 individuals from the UK Biobank
The metabolomic profile of aging is complex. Here, we analyse 325 nuclear magnetic
resonance (NMR) biomarkers from 250,341 UK Biobank participants, identifying 54 …
resonance (NMR) biomarkers from 250,341 UK Biobank participants, identifying 54 …
Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study
E Friligkou, S Løkhammer, B Cabrera-Mendoza… - Nature Genetics, 2024 - nature.com
We leveraged information from more than 1.2 million participants, including 97,383 cases, to
investigate the genetics of anxiety disorders across five continental groups. Through …
investigate the genetics of anxiety disorders across five continental groups. Through …
Metabolomic age (MileAge) predicts health and life span: A comparison of multiple machine learning algorithms
Biological aging clocks produce age estimates that can track with age-related health
outcomes. This study aimed to benchmark machine learning algorithms, including …
outcomes. This study aimed to benchmark machine learning algorithms, including …
To be frail or not to be frail: this is the question—a critical narrative review of frailty
S Sciacchitano, V Carola, G Nicolais… - Journal of Clinical …, 2024 - mdpi.com
Many factors have contributed to rendering frailty an emerging, relevant, and very popular
concept. First, many pandemics that have affected humanity in history, including COVID-19 …
concept. First, many pandemics that have affected humanity in history, including COVID-19 …
Adherence to the EAT-lancet diet and incident depression and anxiety
X Lu, L Wu, L Shao, Y Fan, Y Pei, X Lu, Y Borné… - Nature …, 2024 - nature.com
High-quality diets have been increasingly acknowledged as a promising candidate to
counter the growing prevalence of mental health disorders. This study aims to investigate …
counter the growing prevalence of mental health disorders. This study aims to investigate …
Severe mental illness, race/ethnicity, multimorbidity and mortality following COVID-19 infection: nationally representative cohort study
BackgroundThe association of COVID-19 with death in people with severe mental illness
(SMI), and associations with multimorbidity and ethnicity, are unclear. AimsTo determine all …
(SMI), and associations with multimorbidity and ethnicity, are unclear. AimsTo determine all …
Geroscience-centric perspective for geriatric psychiatry: integrating aging biology with geriatric mental health research
The geroscience hypothesis asserts that physiological aging is caused by a small number of
biological pathways. Despite the explosion of geroscience research over the past couple of …
biological pathways. Despite the explosion of geroscience research over the past couple of …
Brain stimulation treatment for bipolar disorder
J Mutz - Bipolar Disorders, 2023 - Wiley Online Library
Aims Bipolar disorders are clinically complex, chronic and recurrent disorders. Few
treatment options are effective across hypomanic, manic, depressive and mixed states and …
treatment options are effective across hypomanic, manic, depressive and mixed states and …