Human retinal dystrophies and degenerations and light-induced retinal degenerations in
animal models are sharing an important feature: visual cell death by apoptosis. Studying …

Photoreceptor cell death is the ultimate cause of vision loss in various retinal disorders,
including retinal detachment (RD). Photoreceptor cell death has been thought to occur …

Cell death in neurodegenerative diseases is often thought to be governed by apoptosis;
however, an increasing body of evidence suggests the involvement of alternative cell death …

Photoreceptor cell death is the major hallmark of a group of human inherited retinal
degenerations commonly referred to as retinitis pigmentosa (RP). Although the causative …

Programmed cell death (PCD) is essential for normal development and maintenance of
tissue homeostasis in multicellular organisms. While it is now evident that PCD can take …

purpose. To test the hypothesis that oxidative injury to the retinal pigment epithelium (RPE)
may lead to retinal damage similar to that associated with the early stages of age-related …

Retinitis pigmentosa comprises a group of inherited retinal photoreceptor degenerations that
lead to progressive loss of vision. Although in most cases rods, but not cones, harbor the …

Retinal cone photoreceptors mediate fine visual acuity, daylight vision, and color vision.
Congenital hereditary conditions in which there is a lack of cone function in humans cause …

Molecular mechanisms underlying apoptosis in retinitis pigmentosa, as in other
neurodegenerative diseases, are still elusive, and this fact hampers the development of a …

Mouse models of retinal degeneration are useful tools to study therapeutic approaches for
patients affected by hereditary retinal dystrophies. We have studied degeneration in the rd10 …