Customized materials-assisted microorganisms in tumor therapeutics

QW Chen, JY Qiao, XH Liu, C Zhang… - Chemical Society …, 2021 - pubs.rsc.org
Microorganisms have been extensively applied as active biotherapeutic agents or drug
delivery vehicles for antitumor treatment because of their unparalleled bio-functionalities …

[HTML][HTML] Tight junction proteins

L Gonzalez-Mariscal, A Betanzos, P Nava… - Progress in biophysics …, 2003 - Elsevier
A fundamental function of epithelia and endothelia is to separate different compartments
within the organism and to regulate the exchange of substances between them. The tight …

Non-coding RNAs participate in the regulatory network of CLDN4 via ceRNA mediated miRNA evasion

Y Song, J Sun, J Zhao, Y Yang, J Shi, Z Wu… - Nature …, 2017 - nature.com
Thousands of genes have been well demonstrated to play important roles in cancer
progression. As genes do not function in isolation, they can be grouped into “networks” …

Claudins and other tight junction proteins

D Günzel, M Fromm - Comprehensive Physiology, 2012 - Wiley Online Library
Epithelial transport relies on the proper function and regulation of the tight junction (TJ),
other‐wise uncontrolled paracellular leakage of solutes and water would occur. They also …

Claudins and epithelial paracellular transport

CM Van Itallie, JM Anderson - Annu. Rev. Physiol., 2006 - annualreviews.org
▪ Abstract Tight junctions form continuous intercellular contacts controlling solute movement
through the paracellular pathway across epithelia. Paracellular barriers vary among …

Translation of microarray data into clinically relevant cancer diagnostic tests using gene expression ratios in lung cancer and mesothelioma

GJ Gordon, RV Jensen, LL Hsiao, SR Gullans… - Cancer research, 2002 - AACR
The pathological distinction between malignant pleural mesothelioma (MPM) and
adenocarcinoma (ADCA) of the lung can be cumbersome using established methods. We …

Tight junctions and the modulation of barrier function in disease

C Förster - Histochemistry and cell biology, 2008 - Springer
Tight junctions create a paracellular barrier in epithelial and endothelial cells protecting
them from the external environment. Two different classes of integral membrane proteins …

[HTML][HTML] Loss of tight junction barrier function and its role in cancer metastasis

TA Martin, WG Jiang - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2009 - Elsevier
As the most apical structure between epithelial and endothelial cells, tight junctions (TJ) are
well known as functioning as a control for the paracellular diffusion of ions and certain …

Claudin proteins in human cancer: promising new targets for diagnosis and therapy

PJ Morin - Cancer research, 2005 - AACR
The tight junction proteins claudins are abnormally regulated in several human cancers. In
particular, claudin-3 and claudin-4 are frequently overexpressed in several neoplasias …

Clostridium perfringens Enterotoxin: Action, Genetics, and Translational Applications

JC Freedman, A Shrestha, BA McClane - Toxins, 2016 - mdpi.com
Clostridium perfringens enterotoxin (CPE) is responsible for causing the gastrointestinal
symptoms of several C. perfringens food-and nonfood-borne human gastrointestinal …