Psychotropic medication non-adherence and its associated factors among patients with major psychiatric disorders: a systematic review and meta-analysis

A Semahegn, K Torpey, A Manu, N Assefa, G Tesfaye… - Systematic reviews, 2020 - Springer
Background Major psychiatric disorders are growing public health concern that attributed
14% of the global burden of diseases. The management of major psychiatric disorders is …

Long-acting injectable versus oral antipsychotics for the maintenance treatment of schizophrenia: a systematic review and comparative meta-analysis of randomised …

T Kishimoto, K Hagi, S Kurokawa, JM Kane… - The Lancet …, 2021 - thelancet.com
Background Evidence of comparative benefits of long-acting injectable antipsychotics (LAIs)
versus oral antipsychotics for schizophrenia has been inconsistent across study designs …

World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of schizophrenia, part 2: update 2012 on the long-term treatment of …

A Hasan, P Falkai, T Wobrock… - The world journal of …, 2013 - Taylor & Francis
These updated guidelines are based on a first edition of the World Federation of Societies of
Biological Psychiatry (WFSBP) guidelines for biological treatment of schizophrenia …

The role of long-acting injectable antipsychotics in schizophrenia: a critical appraisal

S Brissos, MR Veguilla, D Taylor… - Therapeutic …, 2014 - journals.sagepub.com
Despite their widespread use, long-acting injectable (LAI) antipsychotics (APs) are often
regarded with some negativity because of the assumption of punishment, control and …

Effectiveness of long-acting injectable vs oral antipsychotics in patients with schizophrenia: a meta-analysis of prospective and retrospective cohort studies

T Kishimoto, K Hagi, M Nitta, S Leucht… - Schizophrenia …, 2018 - academic.oup.com
Compared with oral antipsychotics (OAPs), long-acting injectable antipsychotics (LAIs)
should improve medication adherence and reduce relapses in schizophrenia. However …

Prediction of disability in schizophrenia: Symptoms, cognition, and self-assessment

PD Harvey, MT Strassnig… - Journal of Experimental …, 2019 - journals.sagepub.com
Schizophrenia is associated with wide-ranging disability across multiple functional domains.
There are several determinants of disability that have been identified to date, including …

Definitions and drivers of relapse in patients with schizophrenia: a systematic literature review

JM Olivares, J Sermon, M Hemels… - Annals of general …, 2013 - Springer
Relapse in patients with schizophrenia has devastating repercussions, including worsening
symptoms, impaired functioning, cognitive deterioration and reduced quality of life. This …

Impact of long-acting injectable antipsychotics on medication adherence and clinical, functional, and economic outcomes of schizophrenia

G Kaplan, J Casoy, J Zummo - Patient preference and adherence, 2013 - Taylor & Francis
Schizophrenia is a debilitating chronic disease that requires lifelong medical care and
supervision. Even with treatment, the majority of patients relapse within 5 years, and suicide …

[HTML][HTML] Efficacy and effectiveness of depot versus oral antipsychotics in schizophrenia: synthesizing results across different research designs

NY Kirson, PJ Weiden, S Yermakov… - The Journal of clinical …, 2013 - psychiatrist.com
Objective: Nonadherence is a major challenge in schizophrenia treatment. While long-acting
(depot) antipsychotic medications are often recommended to address adherence problems …

Risperidone long-acting injectable monotherapy in the maintenance treatment of bipolar I disorder

JA Quiroz, LN Yatham, JM Palumbo, K Karcher… - Biological …, 2010 - Elsevier
BACKGROUND: Treatment adherence is a significant problem in patients with bipolar
disorder. This study was designed to determine the efficacy of risperidone long-acting …