Next-Generation Morphometry for pathomics-data mining in histopathology

DL Hölscher, N Bouteldja, M Joodaki, ML Russo… - Nature …, 2023 - nature.com
Pathology diagnostics relies on the assessment of morphology by trained experts, which
remains subjective and qualitative. Here we developed a framework for large-scale …

Digital staining in optical microscopy using deep learning-a review

L Kreiss, S Jiang, X Li, S Xu, KC Zhou, KC Lee… - PhotoniX, 2023 - Springer
Until recently, conventional biochemical staining had the undisputed status as well-
established benchmark for most biomedical problems related to clinical diagnostics …

[HTML][HTML] Application of digital pathology and machine learning in the liver, kidney and lung diseases

B Wu, G Moeckel - Journal of Pathology Informatics, 2023 - Elsevier
The development of rapid and accurate Whole Slide Imaging (WSI) has paved the way for
the application of Artificial Intelligence (AI) to digital pathology. The availability of WSI in the …

[HTML][HTML] CXCL12 derived from CD248-expressing cancer-associated fibroblasts mediates M2-polarized macrophages to promote nonsmall cell lung cancer …

J Wu, X Liu, J Wu, C Lou, Q Zhang, H Chen… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Nonsmall cell lung cancer (NSCLC) is among the most prevalent malignant tumours
threatening human health. In the tumour microenvironment (TME), cancer-associated …

[HTML][HTML] The Banff 2022 Kidney Meeting Work Plan: data-driven refinement of the Banff Classification for renal allografts

C Roufosse, M Naesens, M Haas, C Lefaucheur… - American journal of …, 2024 - Elsevier
Abstract The XVIth Banff Meeting for Allograft Pathology was held in Banff, Alberta, Canada,
from September 19 to 23, 2022, as a joint meeting with the Canadian Society of …

Understanding fibrosis pathogenesis via modeling macrophage-fibroblast interplay in immune-metabolic context

E Setten, A Castagna, JM Nava-Sedeño… - Nature …, 2022 - nature.com
Fibrosis is a progressive biological condition, leading to organ dysfunction in various clinical
settings. Although fibroblasts and macrophages are known as key cellular players for …

Evaluating tubulointerstitial compartments in renal biopsy specimens using a deep learning-based approach for classifying normal and abnormal tubules

S Hara, E Haneda, M Kawakami, K Morita, R Nishioka… - PloS one, 2022 - journals.plos.org
Renal pathology is essential for diagnosing and assessing the severity and prognosis of
kidney diseases. Deep learning-based approaches have developed rapidly and have been …

Advances in signal amplification strategies applied in pathogenic bacteria apta-sensing analysis—A review

M Liu, S Dou, F Vriesekoop, L Geng, S Zhou… - Analytica Chimica …, 2023 - Elsevier
Pathogenic bacteria are primarily kinds of food hazards that provoke serious harm to human
health via contaminated or spoiled food. Given that pathogenic bacteria continue to …

The potential of artificial intelligence-based applications in kidney pathology

RD Büllow, JN Marsh, SJ Swamidass… - Current opinion in …, 2022 - journals.lww.com
AI applied to image analysis in nephropathology has potential to transform the field by
improving diagnostic accuracy and reproducibility, efficiency, and prognostic power …

Pathological digital biomarkers: validation and application

Y Song, K Kang, I Kim, TJ Kim - Applied Sciences, 2022 - mdpi.com
Digital pathology offers powerful tools for biomarker discovery, analysis, and translation.
Despite its advantages, the clinical adoption of digital pathology has been slow. A clinical …