Unraveling plant natural chemical diversity for drug discovery purposes

E Lautié, O Russo, P Ducrot, JA Boutin - Frontiers in pharmacology, 2020 - frontiersin.org
The screening and testing of extracts against a variety of pharmacological targets in order to
benefit from the immense natural chemical diversity is a concern in many laboratories …

Recent advances in the synthesis and applications of β-keto sulfones: new prospects for the synthesis of β-keto thiosulfones

RJ Reddy, AH Kumari, JJ Kumar - Organic & Biomolecular Chemistry, 2021 - pubs.rsc.org
This review mainly focuses on recent developments in the preparation of β-keto sulfones
and their extensive synthetic applications. New prospects for the synthesis of β-keto …

Electrochemically Induced Regio‐ and Stereoselective (E)‐β‐C(sp2)−H Trifluoromethylation and Arylsulfonylation of Enamides

F Zhang, X Zhao, J Zhang, L Zhao, L Li… - Advanced Synthesis …, 2022 - Wiley Online Library
Herein, we disclosed an electrochemically induced method for the regio‐and stereoselective
(E)‐β‐C (sp2)− H trifluoromethylation of enamides by employing readily available and …

Electrochemical synthesis of β-ketosulfones from switchable starting materials

I Yavari, S Shaabanzadeh - Organic letters, 2020 - ACS Publications
A synthesis of β-ketosulfones via sulfination of aryl methyl ketones and aryl acetylenes with
sodium sulfinates under mild electrochemical conditions, in moderate to good chemical …

Natural products with 1, 2-oxazine scaffold: occurrence, chemical diversity, bioactivity, synthesis, and biosynthesis

LH Yan, X Li, BG Wang - Natural Product Reports, 2023 - pubs.rsc.org
Covering: up to the end of July, 2023 1, 2-Oxazine is a heterocyclic scaffold rarely found in
natural products and is characterized by a directly connected N–O bond in a six-membered …

Diastereoselective organophotocatalytic hydrosulfonylation of cyclopropenes

P Chandu, S Biswas, S Garai, D Sureshkumar - Green Chemistry, 2023 - pubs.rsc.org
Herein, we present a remarkably efficient, highly diastereoselective organophotoredox-
catalyzed hydrosulfonylation of cyclopropenes. This method employs sodium sulfinates to …

Flavin-Dependent Monooxygenase-Mediated 1,2-Oxazine Construction via Meisenheimer Rearrangement in the Biosynthesis of Paeciloxazine

D Yan, K Wang, S Bai, B Liu, J Bai, X Qi… - Journal of the American …, 2022 - ACS Publications
The [1, 2]-Meisenheimer rearrangement is well known as the [1, 2]-migration of an O-
substituted hydroxylamine from a tertiary amine N-oxide, and it is frequently employed in …

Recent progress on anti-Candida natural products

SUN Fu-Juan, LI Min, GU Liang, W Ming-Ling… - Chinese Journal of …, 2021 - Elsevier
Candida is an intractable life-threatening pathogen. Candida infection is extremely difficult to
eradicate, and thus is the major cause of morbidity and mortality in immunocompromised …

Phenanthrene Derivatives from Asarum heterotropoides Showed Excellent Antibacterial Activity against Phytopathogenic Bacteria

X Fan, D Kong, S He, J Chen, Y Jiang… - Journal of Agricultural …, 2021 - ACS Publications
Asarum heterotropoides extracts showed strong antibacterial activity against selected
phytopathogenic bacteria. Bioguided isolation was conducted to obtain 11 phenanthrene …

Biological Activities of Organic Extracts of the Genus Aristolochia: A Review from 2005 to 2021

MA Lerma-Herrera, L Beiza-Granados… - Molecules, 2022 - mdpi.com
Different ethnomedicinal studies have investigated the relationship between various
phytochemicals as well as organic extracts and their bioactive aspects. Studies on biological …