Targeting autophagy, oxidative stress, and ER stress for neurodegenerative disease treatment

Y Esmaeili, Z Yarjanli, F Pakniya, E Bidram… - Journal of Controlled …, 2022 - Elsevier
Protein homeostasis is a vital process for cell function and, therefore, disruption of the
molecular mechanisms involved in this process, such as autophagy, may contribute to …

Linking the amyloid, tau, and mitochondrial hypotheses of Alzheimer's disease and identifying promising drug targets

Z Fišar - Biomolecules, 2022 - mdpi.com
Damage or loss of brain cells and impaired neurochemistry, neurogenesis, and synaptic and
nonsynaptic plasticity of the brain lead to dementia in neurodegenerative diseases, such as …

[HTML][HTML] Protective effects of luteolin against amyloid beta-induced oxidative stress and mitochondrial impairments through peroxisome proliferator-activated receptor γ …

Z He, X Li, Z Wang, Y Cao, S Han, N Li, J Cai, S Cheng… - Redox Biology, 2023 - Elsevier
Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by the
deposition of β-amyloid (Aβ) peptides and dysfunction of mitochondrion, which result in …

[HTML][HTML] Functional roles and mechanisms of ginsenosides from Panax ginseng in atherosclerosis

Q Xue, N He, Z Wang, X Fu, LHH Aung, Y Liu… - Journal of ginseng …, 2021 - Elsevier
Atherosclerosis (AS) is a leading cause of cardiovascular diseases (CVDs) and it results in a
high rate of death worldwide, with an increased prevalence with age despite advances in …

[HTML][HTML] Panax Ginseng in the treatment of Alzheimer's disease and vascular dementia

Z Wang, Z Zhang, J Liu, M Guo, H Li - Journal of Ginseng Research, 2023 - Elsevier
Dementia has become one of the most important diseases threatening human health.
Alzheimer's disease (AD) and vascular dementia (VaD) have the highest incidence rates …

Traditional Chinese medicine for anti-Alzheimer's disease: berberine and evodiamine from Evodia rutaecarpa

Z Fang, Y Tang, J Ying, C Tang, Q Wang - Chinese medicine, 2020 - Springer
Alzheimer's disease (AD) is one of the most common diseases in elderly people with a high
incidence of dementia at approximately 60–80%. The pathogenesis of AD was quite …

Structure characteristics and immunomodulatory activities of a polysaccharide RGRP-1b from radix ginseng Rubra

X Zhang, Z Liu, C Zhong, Y Pu, Z Yang… - International Journal of …, 2021 - Elsevier
The present study was undertaken to explore the structure characteristics, immune
regulation, and anti-cancer abilities of polysaccharides in radix ginseng Rubra (RGR). For …

Regulation of mitochondrial dysfunction induced cell apoptosis is a potential therapeutic strategy for herbal medicine to treat neurodegenerative diseases

RL Li, LY Wang, HX Duan, Q Zhang, X Guo… - Frontiers in …, 2022 - frontiersin.org
Neurodegenerative disease is a progressive neurodegeneration caused by genetic and
environmental factors. Alzheimer's disease (AD), Parkinson's disease (PD), and …

[PDF][PDF] Natural products for attenuating Alzheimer's disease: A narrative review

NT Abdulaziz, FY Al-bazzaz… - Eurasian Chemical …, 2023 - researchgate.net
Alzheimer's disease (AD) is an irreversible (may be fatal) neurological ailment that affects an
increasing number of elderly people. According to research, AD is the most frequent cause …

Therapeutic effects of non-saponin fraction with rich polysaccharide from Korean red ginseng on aging and Alzheimer's disease

SJ Shin, Y Nam, YH Park, MJ Kim, E Lee… - Free Radical Biology …, 2021 - Elsevier
Biological aging provokes morbidity and several functional declines, causing older adults
more susceptible to a variety of diseases than younger adults. In particular, aging is a major …