Multimodal brain and retinal imaging of dopaminergic degeneration in Parkinson disease

JY Lee, A Martin-Bastida, A Murueta-Goyena… - Nature Reviews …, 2022 - nature.com
Parkinson disease (PD) is a progressive disorder characterized by dopaminergic
neurodegeneration in the brain. The development of parkinsonism is preceded by a long …

Past, present and future role of retinal imaging in neurodegenerative disease

AH Kashani, S Asanad, JW Chan, MB Singer… - Progress in retinal and …, 2021 - Elsevier
Retinal imaging technology is rapidly advancing and can provide ever-increasing amounts
of information about the structure, function and molecular composition of retinal tissue in …

Modular machine learning for Alzheimer's disease classification from retinal vasculature

J Tian, G Smith, H Guo, B Liu, Z Pan, Z Wang… - Scientific Reports, 2021 - nature.com
Alzheimer's disease is the leading cause of dementia. The long progression period in
Alzheimer's disease provides a possibility for patients to get early treatment by having …

Retinal layers in Parkinson's disease: a meta-analysis of spectral-domain optical coherence tomography studies

A Chrysou, NM Jansonius, T van Laar - Parkinsonism & related disorders, 2019 - Elsevier
Abstract Background Patients with Parkinson's disease experience visual symptoms,
partially originating from retinal changes. Since 2011, multiple case-control studies using …

Retinal nerve fiber layer thickness changes in Parkinson disease: a meta-analysis

J Yu, Y Feng, Y Xiang, J Huang, G Savini, V Parisi… - PloS one, 2014 - journals.plos.org
Background Parkinson disease (PD) is a neurodegenerative process that leads to a
selective loss of dopaminergic neurons, mainly in the basal ganglia of the brain. Numerous …

Patterns of retinal ganglion cell damage in neurodegenerative disorders: parvocellular vs magnocellular degeneration in optical coherence tomography studies

C La Morgia, L Di Vito, V Carelli, M Carbonelli - Frontiers in neurology, 2017 - frontiersin.org
Many neurodegenerative disorders, such as Parkinson's disease (PD) and Alzheimer's
disease (AD), are characterized by loss of retinal ganglion cells (RGCs) as part of the …

Ocular and visual disorders in Parkinson's disease: common but frequently overlooked

MS Ekker, S Janssen, K Seppi, W Poewe… - Parkinsonism & related …, 2017 - Elsevier
Patients with Parkinson's disease (PD) often compensate for their motor deficits by guiding
their movements visually. A wide range of ocular and visual disorders threatens the patients' …

Structural and functional changes in the retina in Parkinson's disease

JN Alves, BU Westner, A Højlund, RS Weil… - Journal of Neurology …, 2023 - jnnp.bmj.com
Parkinson's disease is caused by degeneration of dopaminergic neurons, originating in the
substantia nigra pars compacta and characterised by bradykinesia, rest tremor and rigidity …

Retinal microvascular network alterations: potential biomarkers of cerebrovascular and neural diseases

D Cabrera DeBuc, GM Somfai… - American Journal of …, 2017 - journals.physiology.org
Increasing evidence suggests that the conditions of retinal microvessels are indicators to a
variety of cerebrovascular, neurodegenerative, psychiatric, and developmental diseases …

Retinal correlates of neurological disorders

TE Yap, SI Balendra, MT Almonte… - … advances in chronic …, 2019 - journals.sagepub.com
Considering the retina as an extension of the brain provides a platform from which to study
diseases of the nervous system. Taking advantage of the clear optical media of the eye and …