The placenta is a transient fetal organ that plays a critical role in the health and wellbeing of
both the fetus and its mother. Functionally, the placenta sustains the growth of the fetus as it …

Strong evidence suggests that early-life exposures to suboptimal environmental factors,
including those in utero, influence our long-term metabolic health. This has been termed …

Maternal-offspring interactions in mammals involve both cooperation and conflict. The fetus
has evolved ways to manipulate maternal physiology to enhance placental nutrient transfer …

Maternal obesity and gestational diabetes mellitus (GDM) are associated with insulin
resistance and health risks for mother and offspring. Obesity is also characterized by low …

Bisphenols and Perfluoroalkyls are chemical compounds widely used in industry known to
be endocrine disruptors (EDs). Once ingested through contaminated aliments, they mimic …

Trophoblast stem (TS) cells were first isolated from the mouse placenta; however, little is
known about their maintenance and niche in vivo. TS cells, like other stem cells, have a …

Conditions such as small for gestational age (SGA), which is defined as birthweight less
than 10th percentile for gestational age can predispose to neurodevelopmental …

The present study investigates the impact of two endocrine disruptors, namely Bisphenols
(BPs) and Perfluoroalkyls (PFs), on human stem cells. These chemicals leach from plastic …

Endocrine disruptors (EDs), such as Bisphenols (BPs) and Perfluoroalkyls (PFs), are a class
of plastic pollutants widely used in industrial applications. Human exposure to these …

Mir483 is a conserved and highly expressed microRNA in placental mammals, embedded
within the Igf2 gene. Its expression is dysregulated in a number of human diseases …