Radiotherapy is used in> 50% of patients with cancer, both for curative and palliative
purposes. Radiotherapy uses ionizing radiation to target and kill tumour tissue, but normal …

The number of patients surviving≥ 5 years after initial cancer diagnosis has significantly
increased during the last decades due to considerable improvements in the treatment of …

The hypothalamus-pituitary-thyroid axis is one of several hormone regulatory systems from
the hypothalamus to the pituitary and ultimately to the peripheral target organs. The …

Purpose For unbiased comparison of different radiation modalities and techniques,
consensus on delineation of radiation sensitive organs at risk (OARs) and on their dose …

Background Gliomas are brain tumours arising from glial cells with an annual incidence of 4
to 11 people per 100,000. In this review we focus on gliomas with low aggressive potential …

The advent of new cancer therapies, alongside expected growth and ageing of the
population, better survival rates and associated costs of care, is uncovering a need to more …

Central hypothyroidism is a rare and heterogeneous disorder that is characterized by a
defect in thyroid hormone secretion in an otherwise normal thyroid gland due to insufficient …

Adrenal insufficiency (AI) is a serious condition, which can arise from pathology affecting the
adrenal gland itself (primary adrenal insufficiency, PAI), hypothalamic or pituitary pathology …

Abstract Purpose Glucocorticoids (GCs), alone or associated to other drugs, were widely
used in the management of patients affected by severe acute respiratory syndrome caused …

Background Patients with low-grade gliomas (LGG) can survive years with their illness.
Proton radiotherapy (PRT) can reduce off-target dose and decrease the risk of treatment …