Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries

H Levine, N Jørgensen… - Human reproduction …, 2023 - academic.oup.com
BACKGROUND Numerous studies have reported declines in semen quality and other
markers of male reproductive health. Our previous meta-analysis reported a significant …

Semen quality in the 21st century

HE Virtanen, N Jørgensen, J Toppari - Nature Reviews Urology, 2017 - nature.com
Although semen quality is an important determinant of fertility, defining clear thresholds for
normal ranges has proven difficult. According to'time to pregnancy'studies, fecundity starts to …

[HTML][HTML] Decline in semen quality among 30,636 young Chinese men from 2001 to 2015

C Huang, B Li, K Xu, D Liu, J Hu, Y Yang, HC Nie… - Fertility and sterility, 2017 - Elsevier
Objective To provide information of semen quality among young Chinese men in the past 15
years. Design Retrospective cross-sectional study. Setting Sperm bank. Patient (s) A total of …

Multiple organ injury in male C57BL/6J mice exposed to ambient particulate matter in a real-ambient PM exposure system in Shijiazhuang, China

D Li, R Zhang, L Cui, C Chu, H Zhang, H Sun… - Environmental …, 2019 - Elsevier
The development of a rodent ambient particulate matter (PM) inhalation system is critical for
drawing causal inferences between PM exposure and the onset of human diseases. In this …

Seasonal variation of semen parameters correlates with environmental temperature and air pollution: A big data analysis over 6 years

D Santi, E Magnani, M Michelangeli, R Grassi… - Environmental …, 2018 - Elsevier
Background Male fertility is progressively declining in many developed countries, but the
relationship between male infertility and environmental factors is still unclear. Objectives To …

Frequency, morbidity and equity—the case for increased research on male fertility

S Kimmins, RA Anderson, CLR Barratt… - Nature Reviews …, 2024 - nature.com
Currently, most men with infertility cannot be given an aetiology, which reflects a lack of
knowledge around gamete production and how it is affected by genetics and the …

Maternal use of mild analgesics during pregnancy associated with reduced anogenital distance in sons: a cohort study of 1027 mother–child pairs

DV Lind, KM Main, HB Kyhl, DM Kristensen… - Human …, 2017 - academic.oup.com
STUDY QUESTION Is maternal use of mild analgesics in pregnancy associated with
anogenital distance (AGD)—the distance from the anus to the genitals—in the offspring …

Environmental pollutants: genetic damage and epigenetic changes in male germ cells

C Vecoli, L Montano, MG Andreassi - Environmental Science and …, 2016 - Springer
About a quarter of the human diseases occurs for exposure to air pollution. The male
reproductive system, and especially spermatogenesis, seems to be particularly sensitive. As …

Sperm quality and environment: a retrospective, cohort study in a Northern province of Italy

D Santi, S Vezzani, ARM Granata, L Roli… - Environmental …, 2016 - Elsevier
Background Several studies proposed a relationship between environmental factors and
semen quality, as well as the negative effect of air pollution on spermatogenesis and …

Estrogenic exposure alters the spermatogonial stem cells in the developing testis, permanently reducing crossover levels in the adult

LA Vrooman, JM Oatley, JE Griswold, TJ Hassold… - PLoS …, 2015 - journals.plos.org
Bisphenol A (BPA) and other endocrine disrupting chemicals have been reported to induce
negative effects on a wide range of physiological processes, including reproduction. In the …