Snake venom peptides and low mass proteins: molecular tools and therapeutic agents

JR Almeida, LM Resende, RK Watanabe… - Current medicinal …, 2017 - ingentaconnect.com
Snake venoms are natural sources of biologically active molecules that are able to act
selectively and specifically on different cellular targets, modulating physiological functions …

Advances in venomics: Modern separation techniques and mass spectrometry

TM Abd El-Aziz, AG Soares, JD Stockand - Journal of Chromatography B, 2020 - Elsevier
Snake venoms are complex chemical mixtures of biologically active proteins and non-
protein components. Toxins have a wide range of targets and effects to include ion channels …

[HTML][HTML] Bothrops atrox, the most important snake involved in human envenomings in the amazon: How venomics contributes to the knowledge of snake biology and …

WM Monteiro, JC Contreras-Bernal, PF Bisneto… - Toxicon: X, 2020 - Elsevier
Bothrops atrox snakes are mostly endemic of the Amazon rainforest and is certainly the
South American pit viper responsible for most of the snakebites in the region. The …

[HTML][HTML] Interpopulational variation and ontogenetic shift in the venom composition of Lataste's viper (Vipera latastei, Boscá 1878) from northern Portugal

I Avella, JJ Calvete, L Sanz, W Wüster, F Licata… - Journal of …, 2022 - Elsevier
Lataste's viper (Vipera latastei) is a venomous European viper endemic to the Iberian
Peninsula, recognised as medically important by the World Health Organization. To date, no …

Venom variation in Bothrops asper lineages from north-western South America

D Mora-Obando, D Salazar-Valenzuela, D Pla… - Journal of …, 2020 - Elsevier
Bothrops asper is a venomous pitviper that is widely distributed and of clinical importance in
Mesoamerica and northern South America, where it is responsible for 50–80% of all …

An in-depth snake venom proteopeptidome characterization: Benchmarking Bothrops jararaca

CA Nicolau, PC Carvalho… - Journal of …, 2017 - Elsevier
A large-scale proteomic approach was devised to advance the understanding of venom
composition. Bothrops jararaca venom was fractionated by OFFGEL followed by …

[HTML][HTML] Comparative gender peptidomics of Bothrops atrox venoms: are there differences between them?

A Simizo, ES Kitano, SS Sant'Anna… - Journal of Venomous …, 2020 - SciELO Brasil
Background: Bothrops atrox is known to be the pit viper responsible for most snakebites and
human fatalities in the Amazon region. It can be found in a wide geographical area including …

[PDF][PDF] Snakebites in the Brazilian Amazon: current knowledge and perspectives

SS de Oliveira, V de Souza Sampaio… - Clin. Toxinol, 2016 - academia.edu
Although important efforts were carried out during the past decades in Brazil to understand
and control snakebite envenomings, important gaps remain for the fulfillment of these goals …

[HTML][HTML] Intraspecific Differences in the Venom of Crotalus durissus cumanensis from Colombia

A Rodríguez-Vargas, N Vega, E Reyes-Montaño… - Toxins, 2022 - mdpi.com
Biochemical and biological differences in the venom of Crotalus durissus cumanensis from
three ecoregions of Colombia were evaluated. Rattlesnakes were collected from the …

Identification of the Molecular Determinants of the Antibacterial Activity of LmutTX, a Lys49 Phospholipase A2 Homologue Isolated from Lachesis muta muta Snake …

R Diniz‐Sousa, CAS Caldeira… - Basic & clinical …, 2018 - Wiley Online Library
Snake venom phospholipases A2 (PLA 2s) are responsible for numerous
pathophysiological effects in snakebites; however, their biochemical properties favour …