Natural killer cell-mediated immune surveillance in cancer: Role of tumor microenvironment
In the immunological surveillance against cancer, natural killer (NK) cells are essential
effectors that help eradicate altered cells. The complex interactions that occur between NK …
effectors that help eradicate altered cells. The complex interactions that occur between NK …
The SARIFA biomarker in the context of basic research of lipid-driven cancers
B Märkl, NG Reitsam, P Grochowski… - NPJ Precision …, 2024 - nature.com
SARIFA was very recently introduced as a histomorphological biomarker with strong
prognostic power for colorectal, gastric, prostate, and pancreatic cancer. It is characterized …
prognostic power for colorectal, gastric, prostate, and pancreatic cancer. It is characterized …
[HTML][HTML] Artificial intelligence in colorectal cancer: from patient screening over tailoring treatment decisions to identification of novel biomarkers
Background: Artificial intelligence (AI) is increasingly entering and transforming not only
medical research but also clinical practice. In the last 10 years, new AI methods have …
medical research but also clinical practice. In the last 10 years, new AI methods have …
Converging deep learning and human-observed tumor-adipocyte interaction as a biomarker in colorectal cancer
NG Reitsam, B Grosser, DF Steiner… - Communications …, 2024 - nature.com
Abstract Background Tumor-Adipose-Feature (TAF) as well as SARIFA (Stroma AReactive
Invasion Front Areas) are two histologic features/biomarkers linking tumor-associated …
Invasion Front Areas) are two histologic features/biomarkers linking tumor-associated …
Predicting lymph node recurrence in cT1‐2N0 tongue squamous cell carcinoma: collaboration between artificial intelligence and pathologists
M Adachi, T Taki, M Kojima, N Sakamoto… - The Journal of …, 2024 - Wiley Online Library
Researchers have attempted to identify the factors involved in lymph node recurrence in cT1‐
2N0 tongue squamous cell carcinoma (SCC). However, studies combining histopathological …
2N0 tongue squamous cell carcinoma (SCC). However, studies combining histopathological …
SARIFA as a new histopathological biomarker is associated with adverse clinicopathological characteristics, tumor-promoting fatty-acid metabolism, and might predict …
JS Enke, M Groß, B Grosser, E Sipos, J Steinestel… - BMC cancer, 2024 - Springer
Abstract Background Recently, we introduced Stroma-AReactive-Invasion-Front-Areas
(SARIFA) as a novel hematoxylin–eosin (H&E)-based histopathologic prognostic biomarker …
(SARIFA) as a novel hematoxylin–eosin (H&E)-based histopathologic prognostic biomarker …
[HTML][HTML] Local Invasion Patterns Characterized by SARIFA and Tumor Budding Differ and Have Distinct Prognostic Significance in Esophageal Adenocarcinoma and …
Á Jakab, L Zarándy, I Kocsmár, T Várkonyi, I Kenessey… - Cancers, 2024 - mdpi.com
Simple Summary Tumor budding (TB), poorly differentiated clusters (PDCs), and the Stroma
AReactive Invasion Front Area (SARIFA) are emerging biomarkers offering fast and cost …
AReactive Invasion Front Area (SARIFA) are emerging biomarkers offering fast and cost …
Stroma AReactive Invasion Front Areas (SARIFA) predict poor survival in adenocarcinomas of the stomach and gastrooesophageal junction: a validation study
D Ulase, HM Behrens, C Röcken - Virchows Archiv, 2024 - Springer
Recently, the presence of “Stroma AReactive Invasion Front Areas”(SARIFA) has been
described as a promising adverse prognostic factor in gastric cancer. However, the validity …
described as a promising adverse prognostic factor in gastric cancer. However, the validity …
SARIFA–ein neuer entitätenübergreifender Biomarker
B Grosser, NG Reitsam, P Grochowski, L Rentschler… - Die Pathologie, 2024 - Springer
SARIFA (Akronym für „Stroma Areactive Invasion Front Areas “) ist ein neuer prognostischer
Biomarker in Karzinomen. Im Wesentlich beschreibt SARIFA das Auftreten eines direkten …
Biomarker in Karzinomen. Im Wesentlich beschreibt SARIFA das Auftreten eines direkten …