The role of lipopolysaccharide-induced cell signalling in chronic inflammation

MJ Page, DB Kell, E Pretorius - Chronic Stress, 2022 - journals.sagepub.com
Lipopolysaccharide (LPS) is the main structural component of the outer membrane of most
Gram-negative bacteria and has diverse immunostimulatory and procoagulant effects. Even …

Oral inflammatory diseases and systemic inflammation: role of the macrophage

H Hasturk, A Kantarci, TE Van Dyke - Frontiers in immunology, 2012 - frontiersin.org
Inflammation is a complex reaction to injurious agents and includes vascular responses,
migration, and activation of leukocytes. Inflammation starts with an acute reaction, which …

The emerging role of curcumin in the modulation of TLR-4 signaling pathway: focus on neuroprotective and anti-rheumatic properties

MA Panaro, A Corrado, T Benameur, CF Paolo… - International Journal of …, 2020 - mdpi.com
Natural products have been used in medicine for thousands of years. Given their potential
health benefits, they have gained significant popularity in recent times. The administration of …

Extracellular vesicles mediate mesenchymal stromal cell-dependent regulation of B cell PI3K-AKT signaling pathway and actin cytoskeleton

A Adamo, J Brandi, S Caligola, P Delfino… - Frontiers in …, 2019 - frontiersin.org
Mesenchymal stromal cells (MSCs) are adult, multipotent cells of mesodermal origin
representing the progenitors of all stromal tissues. MSCs possess significant and broad …

Polysaccharides From Chrysanthemum morifolium Ramat Ameliorate Colitis Rats via Regulation of the Metabolic Profiling and NF-κ B/TLR4 and IL-6/JAK2/STAT3 …

JH Tao, JA Duan, W Zhang, S Jiang, JM Guo… - Frontiers in …, 2018 - frontiersin.org
Studies have indicated that Chrysanthemum polysaccharides (CP) could prominently
ameliorate colitis rats, but its possible mechanism remains unclear. In this study, the …

[HTML][HTML] An integrated transcriptomic and proteomic analysis of sea star epidermal secretions identifies proteins involved in defense and adhesion

E Hennebert, B Leroy, R Wattiez, P Ladurner - Journal of proteomics, 2015 - Elsevier
Sea stars rely on epidermal secretions to cope with their benthic life. Their integument
produces a mucus, which represents the first barrier against invaders; and their tube feet …

The role of lipopolysaccharide‐binding protein in innate immunity: a revisit and its relevance to oral/periodontal health

PH Ding, LJ Jin - Journal of periodontal research, 2014 - Wiley Online Library
Lipopolysaccharide (LPS)‐binding protein (LBP) functions as an acute phase protein and
plays a key role in the innate immune response to bacterial challenge. It is a potential acute …

AKAPs integrate genetic findings for autism spectrum disorders

G Poelmans, B Franke, DL Pauls, JC Glennon… - Translational …, 2013 - nature.com
Autism spectrum disorders (ASDs) are highly heritable, and six genome-wide association
studies (GWASs) of ASDs have been published to date. In this study, we have integrated the …

MicroRNA-145-5p and microRNA-320a encapsulated in endothelial microparticles contribute to the progression of vasculitis in acute Kawasaki Disease

H Nakaoka, K Hirono, S Yamamoto, I Takasaki… - Scientific reports, 2018 - nature.com
Kawasaki Disease (KD) is an acute inflammatory disease that takes the form of systemic
vasculitis. Endothelial microparticles (EMPs) have been recognized as an important …

Ezrin drives adaptation of monocytes to the inflamed lung microenvironment

R Gudneppanavar, C Di Pietro, HH Öz, PX Zhang… - Cell Death & …, 2024 - nature.com
Ezrin, an actin-binding protein, orchestrates the organization of the cortical cytoskeleton and
plasma membrane during cell migration, adhesion, and proliferation. Its role in monocytes …