Beta-blocker and calcium-channel blocker toxicity: current evidence on evaluation and management

CE Goldfine, A Troger, TB Erickson… - … Heart Journal: Acute …, 2024 - academic.oup.com
Beta-blocker and calcium-channel blocker overdoses are associated with severe morbidity
and mortality; therefore, it is important to recognize and appropriately treat individuals with …

Efficacy of lipid emulsion therapy in treating cardiotoxicity from diphenhydramine ingestion: a review and analysis of case reports

J Clemons, A Jandu, B Stein, M Chary - Clinical Toxicology, 2022 - Taylor & Francis
Introduction Lipid emulsion therapy (LET) has been most thoroughly studied to reverse local
anesthetic systemic toxicity (LAST). Case reports suggest that LET can successfully rescue …

Lipid emulsion for xenobiotic overdose: PRO

MR Fettiplace, G Weinberg - British journal of clinical …, 2023 - Wiley Online Library
Infusion of lipid emulsion for drug overdose arose as a treatment for local anaesthetic
systemic toxicity (LAST) initially based on laboratory results in animal models with the …

Conventional treatment of a metaldehyde-intoxicated cat with additional use of low-dose intravenous lipid emulsion

I Bergamini, C Mattavelli, G Grossi… - Journal of Feline …, 2020 - journals.sagepub.com
Case summary An adult male intact domestic shorthair cat was presented for acute onset of
generalised tremors, stupor, horizontal nystagmus, anisocoria and bilateral absence of …

Clinical effects and adverse effects of intravenous lipid emulsion treatment in dogs and cats with suspected poisoning

D Kiwitz, C Markert, R Dörfelt - Plos one, 2024 - journals.plos.org
This retrospective study aimed to evaluate the effects on the clinical signs of poisoning and
adverse effects of intravenous lipid emulsion treatment in 82 animals (dogs and cats) with …

Adverse events associated with a large dose of intravenous lipid emulsion for suspected local anesthetic toxicity

DJ Corwin, A Topjian, BL Banwell… - Clinical …, 2017 - Taylor & Francis
Background: Intravenous lipid emulsion (ILE) has gained favor as a rescue treatment for
cardiovascular collapse due to intravenous local anesthetic overdose, however, goals of ILE …

High-dose intravenous lipid emulsion affecting successful initiation of continuous venovenous hemofiltration and extracorporeal membrane oxygenation

JH Sin, A Tom, A Toyoda, N Roy, BD Hayes - Clinical Toxicology, 2018 - Taylor & Francis
An unidentified middle-aged female suffered a pulseless electrical activity (PEA) arrest after
presumably ingesting unknown amounts of diltiazem extended-release, digoxin, and …

Fat overload syndrome following intravenous lipid emulsion administration as antidote in suspected anesthetic intoxication: insights from a clinical and forensic case …

M Di Paolo, A Maiese, A Scatena… - La Clinica …, 2024 - clinicaterapeutica.it
Medication errors pose significant risks to patients' health, representing a relevant social and
economic issue for the healthcare system. This study focuses on the life-threatening …

Cardio Protective Effects of Lipid Emulsion against Ropivacaine-Induced Local Anesthetic Systemic Toxicity—An Experimental Study

AE Lazar, S Gurzu, A Kovecsi, M Perian… - Journal of Clinical …, 2022 - mdpi.com
Inadvertent intravascular injection of local anesthetics (LA) during regional anesthesia
causes Local Anesthetic Systemic Toxicity (LAST). Theories of lipid rescue in the case of …

Flecainide toxicity secondary to accidental overdose: a pediatric case report of two brothers

SE Gardner Yelton, JB Leonard… - Case reports in …, 2021 - Wiley Online Library
Flecainide is a class 1C antiarrhythmic with a narrow therapeutic window and thereby a high‐
risk medication for causing acute toxicity. Dysrhythmias secondary to flecainide ingestion …