Radiation dose–volume effects in radiation-induced rectal injury

JM Michalski, H Gay, A Jackson, SL Tucker… - International Journal of …, 2010 - Elsevier
The available dose/volume/outcome data for rectal injury were reviewed. The volume of
rectum receiving≥ 60Gy is consistently associated with the risk of Grade≥ 2 rectal toxicity …

Functional outcomes and complications following radiation therapy for prostate cancer: a critical analysis of the literature

L Budäus, M Bolla, A Bossi, C Cozzarini, J Crook… - European urology, 2012 - Elsevier
CONTEXT: Prostate cancer (PCa) patients have many options within the realms of surgery
or radiation therapy (RT). Technical advancements in RT planning and delivery have …

Evidence behind use of intensity-modulated radiotherapy: a systematic review of comparative clinical studies

L Veldeman, I Madani, F Hulstaert… - The lancet …, 2008 - thelancet.com
Since its introduction more than a decade ago, intensity-modulated radiotherapy (IMRT) has
spread to most radiotherapy departments worldwide for a wide range of indications. The …

Dose–volume effects for normal tissues in external radiotherapy: pelvis

C Fiorino, R Valdagni, T Rancati… - Radiotherapy and …, 2009 - Elsevier
A great deal of quantitative information regarding the dose–volume relationships of pelvic
organs at risk has been collected and analysed over the last 10 years. The need to improve …

Single blind randomized phase III trial to investigate the benefit of a focal lesion ablative microboost in prostate cancer (FLAME-trial): study protocol for a randomized …

IM Lips, UA van der Heide, K Haustermans… - Trials, 2011 - Springer
Background The treatment results of external beam radiotherapy for intermediate and high
risk prostate cancer patients are insufficient with five-year biochemical relapse rates of …

Dose-based radiomic analysis (dosiomics) for intensity modulated radiation therapy in patients with prostate cancer: correlation between planned dose distribution …

Y Murakami, T Soyano, T Kozuka, M Ushijima… - International Journal of …, 2022 - Elsevier
Purpose Although radiation therapy is one of the most significant treatment modalities for
localized prostate cancer, the prognostic factors for biochemical recurrence (BCR) regarding …

Clinical and dosimetric predictors of late rectal syndrome after 3D-CRT for localized prostate cancer: preliminary results of a multicenter prospective study

C Fiorino, G Fellin, T Rancati, V Vavassori… - International Journal of …, 2008 - Elsevier
PURPOSE: To assess the predictors of late rectal toxicity in a prospectively investigated
group of patients treated at 70–80 Gy for prostate cancer (1.8–2 Gy fractions) with three …

[HTML][HTML] Intensity-modulated radiotherapy for prostate cancer

BW Fischer-Valuck, YJ Rao… - … andrology and urology, 2018 - ncbi.nlm.nih.gov
Radiation therapy (RT) is a curative treatment modality for localized prostate cancer. Over
the past two decades, advances in technology and imaging have considerably changed RT …

Patient‐reported outcomes after 3‐dimensional conformal, intensity‐modulated, or proton beam radiotherapy for localized prostate cancer

PJ Gray, JJ Paly, BY Yeap, MG Sanda, HM Sandler… - Cancer, 2013 - Wiley Online Library
BACKGROUND: Recent studies have suggested differing toxicity patterns for patients with
prostate cancer who receive treatment with 3‐dimensional conformal radiotherapy (3DCRT) …

The impact of clinical factors on the development of late radiation toxicity: results from the Medical Research Council RT01 trial (ISRCTN47772397)

GC Barnett, G De Meerleer, SL Gulliford, MR Sydes… - Clinical oncology, 2011 - Elsevier
AIMS: A variety of dosimetric parameters have been shown to influence the incidence of late
radiation toxicity. The effect of other treatment-and patient-related factors is less well …