The comet assay as a rapid test in biomonitoring occupational exposure to DNA-damaging agents and effect of confounding factors

P Møller, LE Knudsen, S Loft, H Wallin - Cancer epidemiology biomarkers & …, 2000 - AACR
Within the last decade, the comet assay has been used with increasing popularity to
investigate the level of DNA damage in terms of strand breaks and alkaline labile sites in …

Molecular epidemiology studies on occupational and environmental exposure to mutagens and carcinogens, 1997-1999.

RJ Srám, B Binková - Environmental health perspectives, 2000 - ehp.niehs.nih.gov
Molecular epidemiology is a new and evolving area of research, combining laboratory
measurement of internal dose, biologically effective dose, biologic effects, and influence of …

Chromosomal aberration and single cell gel electrophoresis (comet) assay in the longitudinal risk assessment of occupational exposure to pesticides

D Zeljezic, V Garaj-Vrhovac - Mutagenesis, 2001 - academic.oup.com
In recent years the use of pesticides in agriculture has been increasing steadily. At present
there are more than 1000 chemicals classified as pesticides. Therefore, the widespread use …

Evaluation of DNA damage in workers occupationally exposed to pesticides using single-cell gel electrophoresis (SCGE) assay: pesticide genotoxicity revealed by …

V Garaj-Vrhovac, D Zeljezic - Mutation Research/Genetic Toxicology and …, 2000 - Elsevier
The comet assay, also called the single-cell gel electrophoresis (SCGE) assay, is a rapid
and sensitive method for the detection of DNA damage (strand breaks and alkali-labile sites) …

Lead induced DNA strand breaks in lymphocytes of exposed workers: role of reactive oxygen species and protein kinase C

ME Fracasso, L Perbellini, S Soldà, G Talamini… - … /Genetic Toxicology and …, 2002 - Elsevier
Lead and lead compounds play a significant role in modern industry; a wide variety of
population is at risk of occupational exposure and lead is suspected to be a human …

The effect of smoking on DNA effects in the comet assay: a meta-analysis

H Hoffmann, J Högel, G Speit - Mutagenesis, 2005 - academic.oup.com
The comet assay (alkaline single-cell gel electrophoresis, SCG or SCGE) is frequently used
in biomonitoring to detect genotoxic effects in humans exposed at the workplace or in their …

The alkaline Comet assay as biomarker in assessment of DNA damage in medical personnel occupationally exposed to ionizing radiation

V Garaj-Vrhovac, N Kopjar - Mutagenesis, 2003 - academic.oup.com
The alkaline Comet assay was selected as a biomarker of exposure to evaluate the ongoing
exposure to ionizing radiation of 50 medical workers occupationally exposed to ionizing …

Assessment of DNA damage by comet assay on frozen total blood: method and evaluation in smokers and non-smokers

I Hininger, A Chollat-Namy, S Sauvaigo… - … /Genetic Toxicology and …, 2004 - Elsevier
This study was undertaken with the aim to develop an optimised protocol for the evaluation
of DNA damage in frozen whole blood. This was achieved by use of the single-cell gel …

The effect of smoking and eating habits on DNA damage in Indian population as measured in the Comet assay

A Dhawan, N Mathur, PK Seth - Mutation Research/Fundamental and …, 2001 - Elsevier
This study was undertaken with the aim of assessing the status of DNA damage in a normal
healthy Indian population. The 62 male volunteers in this study belonged to the smoking …

Assessment of primary, oxidative and excision repaired DNA damage in hospital personnel handling antineoplastic drugs

M Villarini, L Dominici, R Piccinini, C Fatigoni… - …, 2010 - academic.oup.com
Abstract The International Agency for Research on Cancer has classified several
antineoplastic drugs in Group 1 (human carcinogens), among which chlorambucil …