Structural studies of the cystic fibrosis transmembrane conductance regulator (CFTR) are
reviewed. Like many membrane proteins, full-length CFTR has proven to be difficult to …

The cystic fibrosis transmembrane conductance regulator (CFTR) anion channel, crucial to
epithelial salt and water homeostasis, and defective due to mutations in its gene in patients …

Cystic fibrosis (CF) is inherited by CFTR (cystic fibrosis transmembrane conductance
regulator) gene mutations. A variety of mutations have been identified in the CFTR gene that …

Multidrug resistance (MDR) is the major cause, by which cancer cells expel the drugs out,
developing a challenge against the current chemotherapeutic drugs regime. This …

Cystic Fibrosis (CF) is an inherited disease caused by mutations in the cystic fibrosis
transmembrane conductance regulator (CFTR) ion channel. Mutations in CFTR cause …

Short‐term treatment with large doses of corticosteroids can result in acute weakness of
muscles in processes that have not yet been fully characterized. Corticosteroids have been …

Reporting Two Novel Mutations in Two Iranian Families with Cystic Fibrosis, Molecular and
Bioinformatic Analysis - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

Ion channels serve multiple functions in organisms. Defective ion channel molecules lead to
hundreds of different diseases. This chapter describes the mechanisms of the three most …

The cystic fibrosis transmembrane conductance regulator (CFTR) is the only member of the
ATP-binding cassette (ABC) superfamily that functions as a chloride channel. The predicted …

The two TAP-like genes, AtTAP1 and AtTAP2, belong to the ABC transporter superfamily of
Arabidopsis. AtTAP2/ALS1 has been shown to be important for aluminum metabolism and …