Differential evolution of apoptosis, programmed necrosis, and autophagy, parthanatos is a
form of cell death mediated by poly (ADP-ribose) polymerase 1 (PARP1), which is caused by …

Reactive oxygen species (ROS) are a group of highly reactive chemicals containing oxygen
produced either exogenously or endogenously. ROS are related to a wide variety of human …

Abstract Serotonin or 5-hydroxytryptamine (5-HT) is a neurotransmitter known to affect
emotion, behavior, and cognition, and its effects are mostly studied in neurological diseases …

Here, we demonstrate a previously unknown function for the 70-kDa heat-shock protein
(HSP70) as a cytokine. HSP70 bound with high affinity to the plasma membrane, elicited a …

Nitric oxide, nitric oxide derivatives and reactive oxygen intermediates are toxic molecules of
the immune system which contribute to the control of microbial pathogens and tumors. There …

Purpose: The role of macrophages in tumorigenesis is complex because they can both
prevent and promote tumor development. Experimental Design: Four hundred forty-six …

Purpose We have previously demonstrated a significant negative impact of intratumoral
neutrophils in metastatic renal cell carcinoma. This study assessed intratumoral neutrophils …

Objective: In patients with oral squamous cell carcinoma, a high proportion of T cells in the
tumor undergo apoptosis, which correlates with Fas ligand (FasL) expression on tumor cells …

Traditional herbal medicine provides several remedies for strengthening the body's
resistance to illness through effects on immune system components. This review article …

As our understanding of the molecular mechanisms governing natural killer (NK) cell activity
increases, their potential in cancer immunotherapy is growing increasingly prominent. This …