2. INTRODUCTION The investigation of many fundamental processes in life sciences
requires straightforward tools for fast, sensitive, reliable, and reproducible detection of …

Understanding the relationship between genetic variation and biological function on a
genomic scale is expected to provide fundamental new insights into the biology, evolution …

Single nucleotide polymorphisms (SNPs) are the most frequently occurring genetic variation
in the human genome, with the total number of SNPs reported in public SNP databases …

We report on the development of molecular inversion probe (MIP) genotyping, an efficient
technology for large-scale single nucleotide polymorphism (SNP) analysis. This technique …

2008 NOMINEE The Council on Botanical and Horticultural Libraries Annual Award for a
Significant Work in Botanical or Horticultural Literature From medicinal, industrial, and …

There is an increasing interest in single nucleotide polymorphism (SNP) typing in the
forensic field, not only for the usefulness of SNPs for defining Y chromosome or mtDNA …

Understanding complex functional mechanisms requires the global and parallel analysis of
different cellular processes. DNA microarrays have become synonymous with this kind of …

Scanners for conventional microarrays typically have imaging spot sizes in the range of 3–5
microns, insufficient to resolve the~ 5-micron-spaced features on the randomly assembled …

DNA pooling is a practical way to reduce the cost of large-scale association studies to
identify susceptibility loci for common diseases. Pooling allows allele frequencies in groups …

One of the fruits of the Human Genome Project is the discovery of millions of DNA sequence
variants in the human genome. The majority of these variants are single nucleotide …