An emphasis on the interaction of signaling pathways highlights the role of miRNAs in the etiology and treatment resistance of gastric cancer

D Fathi, MS Elballal, AE Elesawy, AI Abulsoud… - Life Sciences, 2023 - Elsevier
Gastric cancer (GC) is 4th in incidence and mortality rates globally. Several genetic and
epigenetic factors, including microRNAs (miRNAs), affect its initiation and progression …

[HTML][HTML] Recent advances in gastric cancer early diagnosis

L Necula, L Matei, D Dragu, AI Neagu… - World journal of …, 2019 - ncbi.nlm.nih.gov
Gastric cancer (GC) remains an important cause of cancer death worldwide with a high
mortality rate due to the fact that the majority of GC cases are diagnosed at an advanced …

[HTML][HTML] Biomarkers of gastric cancer: Current topics and future perspective

T Matsuoka, M Yashiro - World journal of gastroenterology, 2018 - ncbi.nlm.nih.gov
Gastric cancer (GC) is one of the most prevalent malignant types in the world and an
aggressive disease with a poor 5-year survival. This cancer is biologically and genetically …

Liquid biopsy in gastric cancer: predictive and prognostic biomarkers

Z Zhang, H Wu, W Chong, L Shang, C Jing, L Li - Cell death & disease, 2022 - nature.com
Gastric cancer (GC) is a high-incidence cancer worldwide. Most patients are diagnosed at
an advanced stage, by which time they have limited treatment options and poor prognosis …

How to stomach an epigenetic insult: the gastric cancer epigenome

N Padmanabhan, T Ushijima, P Tan - Nature reviews Gastroenterology …, 2017 - nature.com
Gastric cancer is a deadly malignancy afflicting close to a million people worldwide. Patient
survival is poor and largely due to late diagnosis and suboptimal therapies. Disease …

Circulating DNA as a strong multimarker prognostic tool for metastatic colorectal cancer patient management care

S El Messaoudi, F Mouliere, S Du Manoir… - Clinical Cancer …, 2016 - AACR
Purpose: Circulating cell-free DNA (ccfDNA) is a valuable source of tumor material obtained
from a simple blood sampling that enables noninvasive analysis of the tumor genome. Our …

Molecular and circulating biomarkers of gastric cancer

W Jelski, B Mroczko - International Journal of Molecular Sciences, 2022 - mdpi.com
Gastric cancer (GC)—a common tumor that affects humans worldwide—is highly malignant
with a poor prognosis. GC is frequently not diagnosed until a relatively advanced stage …

Methylated circulating tumor DNA in blood: power in cancer prognosis and response

K Warton, KL Mahon, G Samimi - Endocrine-related cancer, 2016 - erc.bioscientifica.com
The aim of the present study was to perform a systematic review of published studies to
provide a robust estimation of the use of procalcitonin (ProCT) as a diagnostic marker of …

Clinical applications and perspectives of circulating tumor DNA in gastric cancer

JH Li, DY Zhang, JM Zhu, L Dong - Cancer Cell International, 2024 - Springer
Gastric cancer remains a leading cause of cancer-related death worldwide, largely due to
inadequate screening methods, late diagnosis, and limited treatment options. Liquid biopsy …

[HTML][HTML] Epigenetic biomarkers in gastrointestinal cancers: The current state and clinical perspectives

HM Vedeld, A Goel, GE Lind - Seminars in cancer biology, 2018 - Elsevier
Abstract Each year, almost 4.1 million people are diagnosed with gastrointestinal (GI)
cancers. Due to late detection of this disease, the mortality is high, causing approximately 3 …