Prevalence of diabetes, a serious public health problem is rapidly increasing worldwide.
Type-2 diabetes is the common form of diabetes characterized by insulin resistance and …

The pathology of type 2 diabetes is complex, with multiple stages culminating in a functional
β‐cell mass that is insufficient to meet the body's needs. Although the broad outlines of the …

Exosomes are nanosized extracellular vesicles (EVs) that show great promise in tissue
regeneration and injury repair as mesenchymal stem cell (MSC). MSC has been shown to …

Oral peptide or protein delivery is considered a revolutionary alternative to daily
subcutaneous injection; however, major challenges remain in terms of impediments of the …

Aim. Based on the previously established method, we developed a better and stable animal
model of type 2 diabetes mellitus by high-fat diet combined with multiple low-dose STZ …

Vascular endothelial dysfunction is regarded as the initial step of vascular complications in
diabetes mellitus. This study investigated the amelioration of apigenin and naringenin in …

Objective: The present study aims at determining the stability of a popular type 2 diabetes rat
model induced by a high-fat diet combined with a low-dose streptozotocin injection …

Infusion of mesenchymal stem cells (MSCs) has been shown to effectively lower blood
glucose in diabetic individuals, but the mechanism involved could not be adequately …

The epidemic of type 2 diabetes mellitus (T2DM) is fueled by added fructose consumption.
Here, we thus combined high-fat/high-fructose diet, with multiple low-dose injections of …

Administration of rutin (50 and 100 mg/kg) and pioglitazone (10 mg/kg) orally for 3 weeks
treatment significantly improved body weight, reduced plasma glucose and glycosylated …