AC Woods, KJ Norsworthy - Cancers, 2023 - mdpi.com
Simple Summary Differentiation syndrome (DS) is a frequent clinical complication of treatment with all-trans retinoic acid (ATRA) and/or arsenic trioxide (ATO), and is typically …
S Chu, J Bai, X Wang, L Zhang, L Li - Cureus, 2024 - ncbi.nlm.nih.gov
The introduction of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) has transformed the outcome of acute promyelocytic leukemia (APL) from a uniformly fatal disease to one of …
B Barsoum, A Henneman, S Ahmad… - Leukemia & …, 2021 - Taylor & Francis
Arsenic trioxide (ATO) is the backbone of acute promyelocytic leukemia (APL) treatment and is dosed based on weight with no upper limit, therefore obese patients receive large doses …
G Alexandra, C Doran, B Ionescu, MC Stancioaica… - 2023 - preprints.org
The hallmark of acute promyelocytic leukemia (APL) is the presence of the characteristic fusion transcript of the promyelocytic leukemia gene with the retinoic acid receptor α gene …
T Daifu, K Umeda, H Takahashi… - Pediatrics …, 2021 - search.ebscohost.com
The article presents a case study of a 12-year-old female presented to our hospital with spots of subcutaneous bleeding that had been present for 1 week. Topics include the …
S Cingelova, E Mikuskova, L Demitrovicova… - 2024 - researchsquare.com
In all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) treatment of acute promyelocytic leukemia (APL), differentiation syndrome (DS) assumes a distinct identity separate from …
Y Jiang, L Ji - Journal of International Medical Research, 2020 - journals.sagepub.com
A 55-year-old woman developed acute promyelocytic leukaemia during treatment with all- trans-retinoic acid and arsenic trioxide. Initially, she presented with symptoms of epigastric …
A Canbolat, A Baysal, Ö Tosun - Sağlık Bilimlerinde İleri …, 2021 - dergipark.org.tr
In acute promyelocytic leukemia (APL) potentially fatal coagulopathy and hemorrhages remain major causes of induction failure. Serious thrombotic events are frequently reported …
CA Aylin, T Öykü - Journal of Advanced Research in Health …, 2021 - iupress.istanbul.edu.tr
Ölümcül koagulopatiler ve hemorajiler akut promiyelositik lösemide (APL) indüksiyon tedavisine yanıt alınamamasının temel sebeplerini oluşturmaktadır. Ağır trombotik olaylar …