The changing therapeutic landscape of head and neck cancer

JD Cramer, B Burtness, QT Le, RL Ferris - Nature reviews Clinical …, 2019 - nature.com
Head and neck cancers are a heterogeneous collection of malignancies of the upper
aerodigestive tract, salivary glands and thyroid. In this Review, we primarily focus on the …

Oral cavity carcinoma: current management, controversies, and future directions

SB Chinn, JN Myers - Journal of clinical oncology, 2015 - ascopubs.org
Oral cavity carcinoma (OCC) remains a major cause of morbidity and mortality in patients
with head and neck cancer. Although the incidence has decreased over the last decade …

[HTML][HTML] Sentinel European Node Trial (SENT): 3-year results of sentinel node biopsy in oral cancer

C Schilling, SJ Stoeckli, SK Haerle, MA Broglie… - European Journal of …, 2015 - Elsevier
Purpose Optimum management of the N0 neck is unresolved in oral cancer. Sentinel node
biopsy (SNB) can reliably detect microscopic lymph node metastasis. The object of this study …

Elective neck dissection vs observation in early-stage squamous cell carcinoma of the oral tongue with no clinically apparent lymph node metastasis in the neck: a …

S Abu-Ghanem, M Yehuda, NN Carmel… - … –Head & Neck …, 2016 - jamanetwork.com
Importance The elective management of no clinical or radiologic evidence of lymph node
metastasis in the neck (cN0) in early stage T1-T2 oral tongue squamous cell carcinoma …

Diagnostic efficacy of sentinel lymph node biopsy in early oral squamous cell carcinoma: a meta-analysis of 66 studies

M Liu, SJ Wang, X Yang, H Peng - PloS one, 2017 - journals.plos.org
Objectives The diagnostic efficacy of sentinel lymph node biopsy (SLNB) in early oral
squamous cell carcinoma (OSCC) still remains controversial. This meta-analysis was …

Management of neck metastases in head and neck cancer: United Kingdom National Multidisciplinary Guidelines

V Paleri, TG Urbano, H Mehanna… - The Journal of …, 2016 - cambridge.org
This is the official guideline endorsed by the specialty associations involved in the care of
head and neck cancer patients in the UK. A rational plan to manage the neck is necessary …

Epidemiology of squamous cell carcinoma of the lip in the United States: a population-based cohort analysis

AY Han, EC Kuan, J Mallen-St Clair… - … –Head & Neck …, 2016 - jamanetwork.com
Importance Squamous cell carcinoma of the lip (lip SCC) composes more than 25% of all
oral cancers. Most of the demographic and prognostic indicators for lip SCC are only …

Sentinel lymph node biopsy versus elective neck dissection for stage I to II oral cavity cancer

JD Cramer, S Sridharan, RL Ferris, U Duvvuri… - The …, 2019 - Wiley Online Library
Objectives Sentinel lymph node biopsy (SLNB) has been shown to be an accurate
technique for staging the neck in early‐stage oral cavity squamous cell carcinoma (OCSCC) …

Elective neck dissection in T1/T2 oral squamous cell carcinoma with N0 neck: essential or not? A systematic review and meta-analysis

SA Ibrahim, ANA Ahmed, HA Elsersy… - European Archives of Oto …, 2020 - Springer
Introduction Oral squamous cell carcinoma (SCC) is characterized by a high risk of cervical
lymph node metastasis with a high incidence of occult metastasis. A strong debate is still …

Sentinel lymph node biopsy in clinically N0 T1–T2 staged oral cancer: the Dutch multicenter trial

GB Flach, E Bloemena, WMC Klop, RJJ van Es… - Oral oncology, 2014 - Elsevier
Summary Objectives Results of the Dutch multi-institutional trial on sentinel lymph node
(SLN) biopsy in oral cancer. Patients and methods Patients were consecutively enrolled …