The intraocular pressure (IOP) reflects a balance between inflow and outflow of aqueous
humour. A major strategy in the medical treatment of glaucoma is to reduce inflow and …

Aqueous humour (AH) is an important intraocular fluid responsible for the supply of nutrients
to and removal of metabolic wastes from the avascular tissues of the eye. It is also …

The ciliary body is a complex, highly specialized tissue that comprises several cell types.
The ciliary muscle is situated at the base of the ciliary body and ligaments originating in the …

Objectives To determine whether the bovine eye develops elevation of intraocularpressure
(IOP) in response to topical corticosteroid use and to develop areliable model of steroid …

The aqueous humor is formed by the bilayered ciliary epithelium. The pigmented ciliary
epithelium (PE) faces the stroma and the nonpigmented ciliary epithelium (NPE) contacts …

Purpose: To identify processes that contribute to corticosteroid-induced ocular hypertension
and candidate target genes for treatment. Methods: A systematic search identified five …

Glaucoma is an optic neuropathy characterized by progressive degeneration of retinal
ganglion cells (RGCs) and visual loss. Although one of the highest risk factors for glaucoma …

purpose. To investigate the role of active chloride secretion by the ciliary epithelium in the
formation of aqueous humor (AH), by using the in vitro perfused eye. methods. Bovine eyes …

purpose. To test whether blocking the Na+/H+ antiport reduces intraocular pressure (IOP) in
the mouse. methods. The electrophysiologic approach (the servo-null micropipette system …

This article discusses three largely unrecognized aspects related to fluid movement in ocular
tissues; namely,(a) the dynamic changes in water permeability observed in corneal and …