Metabolic reprogramming enables cancer cell growth, proliferation, and survival. This
reprogramming is driven by the combined actions of oncogenic alterations in cancer cells …

In recent years there has been a growing interest among cancer biologists in cancer
metabolism. This Review summarizes past and recent advances in our understanding of the …

Background: Heart failure is a global public health issue that is associated with increasing
morbidity and mortality. Previous studies have suggested that mitochondrial dysfunction …

MicroRNAs (miRNAs) are approximately 22-nucleotide-long, small non-coding RNAs that
post-transcriptionally regulate gene expression. The biogenesis of miRNAs involves multiple …

Cancer cells display a high rate of glycolysis in the presence of oxygen to promote
proliferation. Gluconeogenesis, the reverse pathway of glycolysis, can antagonize aerobic …

Cancer cells constantly face a fluctuating nutrient supply and interference with adaptive
responses might be an effective therapeutic approach. It has been discovered that in the …

Alterations of hepatic metabolism are critical to the development of liver disease. The
peroxisome proliferator-activated receptor-γ coactivators (PGC1s) are able to orchestrate, on …

Cancer reprogramming is an important facilitator of cancer development and survival, with
tumor cells exhibiting a preference for aerobic glycolysis beyond oxidative phosphorylation …

Simple Summary Hepatocellular carcinoma (HCC) is one of the most frequently occurring
cancers, and the prognosis for late-stage HCC remains poor. A better understanding of the …

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer death worldwide.
HCC progression and metastasis are closely related to altered mitochondrial metabolism …