Background Immunotherapy has emerged as a novel strategy for cancer treatment following
surgery, radiotherapy, and chemotherapy. Immune checkpoint blockade and Chimeric …

Low-grade glioma (LGG) is a grade II-III glioma accompanied by distinct clinical and
molecular characteristics and the studies related to its prognosis are still unclear. The …

CD24 is a glycosylphosphatidylinositol-anchored protein that is expressed in a wide range
of tissues and cell types. It is involved in a variety of physiological and pathological …

Purpose Glioma has been demonstrated as one of the most malignant intracranial tumors
and currently there is no effective treatment. Based on our previous RNA-sequencing data …

Macrophages and microglia are professional phagocytes that sense and migrate toward “eat-
me” signals. The role of phagocytic cells is to maintain homeostasis by engulfing senescent …

Background Cancer immunotherapy has emerged as a groundbreaking approach in cancer
treatment, primarily realized through the manipulation of immune cells, notably T cell …

To understand how upregulated isoglutaminyl cyclase (isoQC) is involved in the initiation of
diseases such as cancer, we developed a human KYSE30 carcinoma cell model in which …

Background A subset of neutrophils isolated from the peripheral blood mononuclear cells
(PBMC) layer has recently been described in cancer patients. Methods Double-gradient …

Abstract Background Immune checkpoint blockers (ICBs) plus chemotherapy as
neoadjuvant therapy for patients with esophageal cancer (EC) has gained substantial …

Glutaminyl-peptide cyclotransferase-like protein (QPCTL) is a newly discovered enzyme that
has sparked interest owing to its possible role in cancer genesis and progression. Initially …