The harmful use of alcohol has been estimated to cause approximately 3.3 million deaths
every year, corresponding to nearly 6% of all deaths globally. Therefore, the effective …

Alcohol is a major contributor to global disease and a leading cause of preventable death,
causing approximately 88,000 deaths annually in the United States alone. Alcohol use …

The aim of this updated guideline is to provide comprehensive and timely evidence-based
recommendations on the prevention of future stroke among survivors of ischemic stroke or …

Importance Opioid-dependent patients often use the emergency department (ED) for
medical care. Objective To test the efficacy of 3 interventions for opioid dependence:(1) …

Importance Alcohol use disorders cause substantial morbidity and early mortality yet remain
greatly undertreated. Medications are considerably underused. Objective To conduct a …

Background: Meta-analysis of randomized studies using lysergic acid diethylamide (LSD) for
alcohol use disorder (AUD) showed large, significant effects for LSD efficacy compared to …

Substance use disorders (SUDs) are highly prevalent and exact a large toll on individuals'
health, well‐being, and social functioning. Long‐lasting changes in brain networks involved …

The goal of this guideline1 is to improve the quality of care and treatment outcomes for
patients with alcohol use disorder (AUD), as defined by DSM-5 (American Psychiatric …

This paper reviews the evidence for the effectiveness and cost-effectiveness of policies to
reduce alcohol-related harm. Policies focus on price, marketing, availability, information and …

Background Face-to-face brief interventions for problem drinking are effective, but they have
found limited implementation in routine care and the community. Internet-based …