The assembly of ribosomal subunits is a highly orchestrated process that involves a huge
cohort of accessory factors. Most eukaryotic ribosome biogenesis factors were first identified …

Ribosomes, which synthesize the proteins of a cell, comprise ribosomal RNA and ribosomal
proteins, which coassemble hierarchically during a process termed ribosome biogenesis …

Ribosomes are highly conserved ribonucleoprotein nanomachines that translate information
in the genome to create the proteome in all cells. In yeast these complex particles contain …

Eukaryotic ribosome synthesis is a complex, energy-consuming process that takes place
across the nucleolus, nucleoplasm and cytoplasm and requires more than 200 conserved …

The 90S pre-ribosome is an early biogenesis intermediate formed during co-transcriptional
ribosome formation, composed of∼ 70 assembly factors and several small nucleolar RNAs …

Production of small ribosomal subunits initially requires the formation of a 90 S precursor
followed by an enigmatic process of restructuring into the primordial pre-40 S subunit. We …

Eukaryotic small ribosomal subunits are first assembled into 90S pre-ribosomes. The
complete 90S is a gigantic complex with a molecular mass of approximately five …

The coordinated integration of ribosomal RNA and protein into two functional ribosomal
subunits is safeguarded by quality control checkpoints that ensure ribosomes are correctly …

Eukaryotic ribosome biogenesis involves the synthesis of ribosomal RNA (rRNA) and its
stepwise folding into the unique structure present in mature ribosomes. rRNA folding starts …

The eukaryotic exosome is a ten-subunit 3′ exoribonucleolytic complex responsible for
many RNA-processing and RNA-degradation reactions. How the exosome accomplishes …