Nrf2 and oxidative stress: A general overview of mechanisms and implications in human disease
V Ngo, ML Duennwald - Antioxidants, 2022 - mdpi.com
Organisms are continually exposed to exogenous and endogenous sources of reactive
oxygen species (ROS) and other oxidants that have both beneficial and deleterious effects …
oxygen species (ROS) and other oxidants that have both beneficial and deleterious effects …
Post-COVID-19 depressive symptoms: epidemiology, pathophysiology, and pharmacological treatment
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic is still spreading worldwide
over 2 years since its outbreak. The psychopathological implications in COVID-19 survivors …
over 2 years since its outbreak. The psychopathological implications in COVID-19 survivors …
The role of inflammation in depression and fatigue
CH Lee, F Giuliani - Frontiers in immunology, 2019 - frontiersin.org
Depression and fatigue are conditions responsible for heavy global societal burden,
especially in patients already suffering from chronic diseases. These symptoms have been …
especially in patients already suffering from chronic diseases. These symptoms have been …
The Lancet Commission on global mental health and sustainable development
V Patel, S Saxena, C Lund, G Thornicroft, F Baingana… - The lancet, 2018 - thelancet.com
Executive summary The Sustainable Development Goals (SDGs) represent an exponential
advance from the Millennium Development Goals, with a substantially broader agenda …
advance from the Millennium Development Goals, with a substantially broader agenda …
The kynurenine pathway in major depressive disorder, bipolar disorder, and schizophrenia: a meta-analysis of 101 studies
The importance of tryptophan as a precursor for neuroactive compounds has long been
acknowledged. The metabolism of tryptophan along the kynurenine pathway and its …
acknowledged. The metabolism of tryptophan along the kynurenine pathway and its …
Vagus nerve as modulator of the brain–gut axis in psychiatric and inflammatory disorders
The vagus nerve represents the main component of the parasympathetic nervous system,
which oversees a vast array of crucial bodily functions, including control of mood, immune …
which oversees a vast array of crucial bodily functions, including control of mood, immune …
Markers of central inflammation in major depressive disorder: a systematic review and meta-analysis of studies examining cerebrospinal fluid, positron emission …
D Enache, CM Pariante, V Mondelli - Brain, behavior, and immunity, 2019 - Elsevier
Background Increased peripheral inflammation has been consistently reported in patients
with major depressive disorder (MDD). However, only few studies have explored markers of …
with major depressive disorder (MDD). However, only few studies have explored markers of …
Role of interleukin-6 in depressive disorder
Major depressive disorder (MDD), which is a leading psychiatric illness across the world,
severely affects quality of life and causes an increased incidence of suicide. Evidence from …
severely affects quality of life and causes an increased incidence of suicide. Evidence from …
Psychobiotics and the manipulation of bacteria–gut–brain signals
Psychobiotics were previously defined as live bacteria (probiotics) which, when ingested,
confer mental health benefits through interactions with commensal gut bacteria. We expand …
confer mental health benefits through interactions with commensal gut bacteria. We expand …
Neuroinflammation induces anxiety-and depressive-like behavior by modulating neuronal plasticity in the basolateral amygdala
ZH Zheng, JL Tu, XH Li, Q Hua, WZ Liu, Y Liu… - Brain, behavior, and …, 2021 - Elsevier
Increasing evidence indicates that excessive inflammatory responses play a crucial role in
the pathophysiology of psychiatric diseases, including depression and anxiety disorders …
the pathophysiology of psychiatric diseases, including depression and anxiety disorders …