Objective: Epilepsy is a complex disease spanning across multiple scales, from ion
channels in neurons to neuronal circuits across the entire brain. Over the past decades …

Inspired by the interplay between both electrical and chemical synapses, we propose an
analog electronic synapse-like model to characterize biological synaptic properties. By …

Epilepsy is a debilitating condition, primarily refractory individuals, leading to the search for
new efficient therapies. Electrical stimulation is an important method used for years to treat …

Dynamical modelling for neural systems with direct and indirect connections is to
understand how these connections contribute to neural dynamics. Despite recent findings …

In this paper, we establish a cortical-thalamic-basal ganglia mean-field computational
network that includes a newly determined direct glutamatergic thalamic-subthalamic …

The output of the basal ganglia to the corticothalamic system plays an important role in
regulating absence seizures. Inspired by experiments, we systematically study the crucial …

Waveform transitions have high correlation to spike wave discharges and polyspike wave
discharges in seizure dynamics. This research adopts nonlinear dynamics to study the …

The transiting mechanism of abnormal brain functional activities, such as the epileptic
seizures, has not been fully elucidated. In this study, we employ a probabilistic neural …