Neurodegenerative diseases pose a substantial socioeconomic burden on society.
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …

The Portulaca oleracea L. commonly known as purslane is distributed all over the world and
easily grows in diverse soil and climatic conditions. It has been traditionally used as a …

N‐Heterocyclic carbene (NHC) catalyzed transformations have emerged as powerful tactics
for the construction of complex molecules. Since Stetter's report in 1975 of the total synthesis …

Chroman-4-one scaffold is a privileged structure in heterocyclic chemistry and drug
discovery. Also, chroman-4-ones are important intermediates and interesting building blocks …

Monoamine oxidase is a flavin enzyme that catalyzes the oxidation of monoamine
neurotransmitters in the brain. Various toxic by-products, aldehydes and hydrogen peroxide …

A series of homoisoflavonoid Mannich base derivatives were designed, synthesized and
evaluated as multifunctional agents against Alzheimer's disease. It demonstrated that most …

Carboxylated chalcones and other related flavonoids were synthesized and evaluated as
inhibitors of xanthine oxidase, which is a known target for synthetic and herbal drugs used …

Novel coronavirus, 2019-nCoV is a danger to the world and is spreading rapidly. Very little
structural information about 2019-nCoV make this situation more difficult for drug designing …

In screening experiments for antiacne activity, methanolic and 50% ethanolic extracts of
Caesalpinia sappan wood showed the most potent activity out of 28 species of plants …

A set of twenty-four synthetic derivatives, with coumarin and homoisoflavonoid cores and
structural analogs, were submitted for evaluation of antifungal activity against various …