Inherited retinal dystrophies (IRDs) affect an estimated 1 in every 2000 people, this
corresponding to nearly 2 million cases worldwide. Currently, 270 genes have been …

Breakthroughs with rapid changes are the themes of the development in Neurorestoratology
this year. Given the very difficult circumstances of the persistent COVID-19 pandemic, most …

Developing cellular therapies is not straightforward. This Perspective summarizes the
experience of a group of academic stem cell investigators working in different clinical areas …

Neural stem cells represent an attractive tool for the development of regenerative therapies
and are being tested in clinical trials for several neurological disorders. Human neural stem …

Cell therapies have been explored to treat patients with nervous diseases for over 20 years.
Even though most kinds of cell therapies demonstrated neurorestorative effects in non …

Regenerative medicine (RM) has emerged as a promising and revolutionary solution to
address a range of unmet needs in healthcare, including ophthalmology. Moreover, RM …

Purpose To compare the macular retinal pigment epithelium (RPE) atrophy progression rate
of selected degenerative and macular inherited retinal diseases (IRD). Design Systematic …

Abstract Background Retinal degenerative disorders (RDDs) cause vision loss by damaging
retinal neurons and photoreceptors, affecting individuals of all ages. Cell-based therapy has …

Photoreceptor degeneration is a major cause of untreatable blindness worldwide and has
recently been targeted by emerging technologies, including cell-and gene-based therapies …

Background Stem cell transplantation may improve visual acuity in patients with dry age-
related macular degeneration. Herein, we aimed to summarise the evidence on the risks …