Previous studies have explored the potential of pomace valorization, with an emphasis on
the transformation of polysaccharide biopolymers of pomace-cellulose and hemicellulose to …

We highlight key contributions in the field of direct radical CAr− H (hetero) aromatic
functionalization involving fluorinated radicals. A compilation of Functional Group Transfer …

Hybrid fused two-dimensional/three-dimensional (2D/3D) rings are important
pharmacophores in drugs owing to their unique structural and physicochemical properties …

Cross-coupling reaction between two C–H bonds has become a fundamental strategy in
synthetic organic chemistry. With its increasing importance in green chemistry, atom …

Bioisosterism is a unique approach used by medicinal chemists for the reasonable
modification of lead compounds into safer, more clinically effective, economical, and …

The drug discovery and development (DDD) process in pursuit of novel drug candidates is a
challenging procedure requiring lots of time and resources. Therefore, computer-aided drug …

Benzodiazepines block the activity of nerves in the brain and the central nervous system
whenever it is exceeded. The benzodiazepine derivatives such as CZ and OZ have been …

Positron emission tomography (PET) is a powerful imaging technology that can visualize
and measure metabolic processes in vivo and/or obtain unique information about drug …

Malignant glioblastoma (GB) treatment consists of resection surgery followed by
radiotherapy and chemotherapy (CT). Despite several implications, such as systemic toxicity …

Three prominent health challenges affecting our society include cancer, diabetes, and
antibiotic-resistant infections. Despite the availability of conventional drugs for these …