Current insights in noise-induced hearing loss: a literature review of the underlying mechanism, pathophysiology, asymmetry, and management options

TN Le, LV Straatman, J Lea… - … of otolaryngology-head …, 2017 - journals.sagepub.com
Background Noise-induced hearing loss is one of the most common forms of sensorineural
hearing loss, is a major health problem, is largely preventable and is probably more …

[HTML][HTML] Mechanisms of noise-induced tinnitus: insights from cellular studies

SE Shore, C Wu - Neuron, 2019 - cell.com
Tinnitus, sound perception in the absence of physical stimuli, occurs in 15% of the
population and is the top-reported disability for soldiers after combat. Noise overexposure is …

[HTML][HTML] Loss of auditory sensitivity from inner hair cell synaptopathy can be centrally compensated in the young but not old brain

D Möhrle, K Ni, K Varakina, D Bing, SC Lee… - Neurobiology of …, 2016 - Elsevier
A dramatic shift in societal demographics will lead to rapid growth in the number of older
people with hearing deficits. Poorer performance in suprathreshold speech understanding …

Enhanced central neural gain compensates acoustic trauma-induced cochlear impairment, but unlikely correlates with tinnitus and hyperacusis

D Möhrle, B Hofmeier, M Amend, S Wolpert, K Ni… - Neuroscience, 2019 - Elsevier
For successful future therapeutic strategies for tinnitus and hyperacusis, a subcategorization
of both conditions on the basis of differentiated neural correlates would be of invaluable …

Disturbed balance of inhibitory signaling links hearing loss and cognition

M Knipper, W Singer, K Schwabe… - Frontiers in Neural …, 2022 - frontiersin.org
Neuronal hyperexcitability in the central auditory pathway linked to reduced inhibitory
activity is associated with numerous forms of hearing loss, including noise damage, age …

Depolarization shift in the resting membrane potential of inferior colliculus neurons explains their hyperactivity induced by an acoustic trauma

CJ Hsiao, AV Galazyuk - Frontiers in neuroscience, 2023 - frontiersin.org
Introduction Neuronal hyperactivity has been associated with many brain diseases. In the
auditory system, hyperactivity has been linked to hyperacusis and tinnitus. Previous …

Impact of noise on hearing in the military

JS Yong, DY Wang - Military Medical Research, 2015 - Springer
Hearing plays a vital role in the performance of a soldier and is important for speech
processing. Noise-induced hearing loss is a significant impairment in the military and can …

Central compensation in auditory brainstem after damaging noise exposure

KM Schrode, MA Muniak, YH Kim, AM Lauer - Eneuro, 2018 - eneuro.org
Noise exposure is one of the most common causes of hearing loss and peripheral damage
to the auditory system. A growing literature suggests that the auditory system can …

Developmental exposure to polychlorinated biphenyls prevents recovery from noise-induced hearing loss and disrupts the functional organization of the inferior …

BA Ibrahim, JJ Louie, Y Shinagawa, G Xiao… - Journal of …, 2023 - Soc Neuroscience
Exposure to combinations of environmental toxins is growing in prevalence; and therefore,
understanding their interactions is of increasing societal importance. Here, we examined the …

Cochlear synaptopathy changes sound-evoked activity without changing spontaneous discharge in the mouse inferior colliculus

LA Shaheen, MC Liberman - Frontiers in systems neuroscience, 2018 - frontiersin.org
Tinnitus and hyperacusis are life-disrupting perceptual abnormalities that are often
preceded by acoustic overexposure. Animal models of overexposure have suggested a link …