Benzimidazoles are fused heterocyclic ring systems containing two nitrogen atoms. They
have vital therapeutic significance in drug discovery. Many clinically approved drugs have …

In this 21 st century, Malaria remains a global burden and causes massive economic trouble
to disease-endemic nations. The control and eradication of malaria is a major challenge that …

Abstract Design of tubulin inhibitors as anticancer drugs dynamically developed over the
past 20 years. The modern arsenal of potential tubulin-targeting anticancer agents is …

Replication of the malarial parasite in human erythrocytes requires massive zinc fluxes,
necessitating the action of zinc transporters across the parasite plasma and organellar …

Phthalimides, an important class of biologically active N-heterocycles, are not only found in
pharmaceuticals, natural products, agrochemicals, polymers, and dyes, but also serve as …

Pharmacophores such as hydroxyethylamine (HEA) and phthalimide (PHT) have been
identified as potential synthons for the development of compounds against various parasitic …

The ongoing work delineates the design of a novel library of 1, 2, 3-triazole-attached
phenylacetamides through molecular hybridization of propargyl and phenylacetamide …

Chilodonella, a parasitic ciliate that infects both cold water and warm water fish, can impede
the growth of juvenile fish and cause considerable economic losses globally to freshwater …

As part of ongoing efforts to isolate biologically active fungal metabolites, a cyclic
pentapeptide, sheptide A (1), was discovered from strain MSX53339 (Herpotrichiellaceae) …

An operationally simple three-component coupling of tetrahydroisoquinoline (THIQ),
aldehydes and indoles or indole-3-carboxylic acids has been achieved using chitosan-ionic …