Daptomycin is a cyclic lipopeptide antibiotic, which was discovered in 1987 and entered the
market in 2003. To date, it serves as last resort antibiotic to treat complicated skin infections …

The dramatic rise in the incidence of antibiotic resistance demands that new therapeutic
options will have to be developed. One potentially interesting class of antimicrobials are the …

Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …

Daptomycin is a calcium-dependent cyclic lipodepsipeptide derived from the soil saprotroph
Streptomyces roseosporus, and its antibiotic properties make it a key agent for treatment of …

Bacterial persisters are a sub-population of phenotypic variants that tolerate high
concentrations of antibiotics within the genetically homogeneous cells. They resume division …

Ribosomally synthesized peptides are built out of l-amino acids, whereas d-amino acids are
generally the hallmark of non-ribosomal synthetic processes. Here we show that the model …

Antimicrobial peptides (AMPs) are utilized by both eukaryotic and prokaryotic organisms.
AMPs such as the human beta defensins, human neutrophil peptides, human cathelicidin …

Protection against antimicrobial peptides (AMPs) often involves the parallel production of
multiple, well‐characterized resistance determinants. So far, little is known about how these …

The cell wall is a surface layer located outside the cell membrane of almost all bacteria; it
protects cells from environmental stresses and gives them their typical shape. The cell wall …

The cell envelope stress response (CESR) encompasses all regulatory events that enable a
cell to protect the integrity of its envelope, an essential structure of any bacterial cell. The …